Mesenchymal Stromal Cell Therapy for Thoracic Surgeons: An Update

被引：0

作者：

Petrella, Francesco ^{[1
]}

Cassina, Enrico Mario ^{[1
]}

Libretti, Lidia ^{[1
]}

Pirondini, Emanuele ^{[1
]}

Raveglia, Federico ^{[1
]}

Tuoro, Antonio ^{[1
]}

机构：

[1] Fdn IRCCS San Gerardo Tintori, Dept Thorac Surg, I-20900 Monza, Italy

来源：

JOURNAL OF PERSONALIZED MEDICINE | 2023年 / 13卷 / 12期

关键词：

stromal cell; regenerative medicine; drug loading; drug delivery; oncology; thoracic surgery; bronchopleural fistula; pleural mesothelioma; imaging; lipofilling; LARGE AIRWAY DEFECTS; STEM-CELLS; BRONCHOPLEURAL FISTULA; EXTRACELLULAR VESICLES; BRONCHOSCOPIC TREATMENT; EPITHELIAL-CELLS; REPAIR; MATRIX; TISSUE; DIFFERENTIATION;

D O I：

10.3390/jpm13121632

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Stem cells are undifferentiated cells presenting extensive self-renewal features and the ability to differentiate "in vitro" and "in vivo" into a range of lineage cells, like chondrogenic, osteogenic and adipogenic lineages when cultured in specific inducing media. Two major domains of clinical applications of stem cells in thoracic surgery have been investigated: regenerative medicine, which is a section of translational research in tissue engineering focusing on the replacement, renewal or regeneration of cells, tissues and organs to re-establish damaged physiologic functions; drug loading and delivery, representing a new branch proposing stem cells as carriers to provide selected districts with anti-cancer agents for targeted treatments.

引用

页数：14

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