Circular RNAs: Biogenesis, Biological Functions, and Roles in Myocardial Infarction

被引:19
|
作者
Li, Jialei [1 ]
Han, Yu [1 ]
Wang, Shuang [1 ]
Wu, Xiaolei [1 ]
Cao, Jimin [1 ]
Sun, Teng [1 ]
机构
[1] Shanxi Med Univ, Key Lab Cellular Physiol, Dept Physiol, Key Lab Cellular Physiol Shanxi Prov,Minist Educ, Taiyuan 030001, Peoples R China
基金
中国国家自然科学基金;
关键词
circular RNAs; biogenesis; cyclization form; biological functions; myocardial infarction; ISCHEMIA-REPERFUSION INJURY; GENE-EXPRESSION; TROPONIN-I; TRANSCRIPTS; APOPTOSIS; PROMOTES; BINDING; RAT;
D O I
10.3390/ijms24044233
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Non-coding RNAs have been excavated as important cardiac function modulators and linked to heart diseases. Significant advances have been obtained in illuminating the effects of microRNAs and long non-coding RNAs. Nevertheless, the characteristics of circular RNAs are rarely mined. Circular RNAs (circRNAs) are widely believed to participate in cardiac pathologic processes, especially in myocardial infarction. In this review, we round up the biogenesis of circRNAs, briefly describe their biological functions, and summarize the latest literature on multifarious circRNAs related to new therapies and biomarkers for myocardial infarction.
引用
收藏
页数:18
相关论文
共 50 条
  • [31] Roles of circular RNAs in colorectal cancer
    Zhang, Mingying
    Wang, Shubin
    ONCOLOGY LETTERS, 2021, 22 (02)
  • [32] Emerging roles and context of circular RNAs
    Panda, Amaresh C.
    Grammatikakis, Ioannis
    Munk, Rachel
    Gorospe, Myriam
    Abdelmohsen, Kotb
    WILEY INTERDISCIPLINARY REVIEWS-RNA, 2017, 8 (02)
  • [33] Emerging roles of circular RNAs in tuberculosis
    Wang, Qinglan
    Yang, Danni
    Zuo, Yinan
    Wang, Dan
    Li, Weimin
    FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [34] The biogenesis, biology and characterization of circular RNAs
    Kristensen, Lasse S.
    Andersen, Maria S.
    Stagsted, Lotte V. W.
    Ebbesen, Karoline K.
    Hansen, Thomas B.
    Kjems, Jorgen
    NATURE REVIEWS GENETICS, 2019, 20 (11) : 675 - 691
  • [35] Circular RNAs: Identification, biogenesis and function
    Ebbesen, Karoline K.
    Kjems, Jorgen
    Hansen, Thomas B.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2016, 1859 (01): : 163 - 168
  • [36] Exploring Cardiac Exosomal RNAs of Acute Myocardial Infarction
    Jung, Seung Eun
    Kim, Sang Woo
    Choi, Jung-Won
    BIOMEDICINES, 2024, 12 (02)
  • [37] Biological roles and potential clinical values of circular RNAs in gastrointestinal malignancies
    Tao, Xueping
    Shao, Yongfu
    Yan, Jianing
    Yang, Liyang
    Ye, Qihua
    Wang, Qingling
    Lu, Rongdan
    Guo, Junming
    CANCER BIOLOGY & MEDICINE, 2021, 18 (02) : 437 - 457
  • [38] Editorial: Emerging Roles of Circular RNAs in the Tumor: Functions and Potential Applications
    Guo, Shanchun
    Huang, Lan
    Liu, Mingli
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2022, 10
  • [39] Emerging roles of circular RNAs in innate immunity
    Li, Isabella
    Chen, Y. Grace
    CURRENT OPINION IN IMMUNOLOGY, 2021, 68 : 107 - 115
  • [40] Circular RNAs and Their Emerging Roles in Immune Regulation
    Yang, Lan
    Fu, Jinrong
    Zhou, Yufeng
    FRONTIERS IN IMMUNOLOGY, 2018, 9