Magnetic Resonance Imaging Features of Rhino-Orbito-Cerebral Mucormycosis in Post-COVID-19 Patients: Radio-Pathological Correlation

被引:2
|
作者
Hassan, Rania Mostafa [1 ]
Almalki, Yassir Edrees [2 ]
Basha, Mohammad Abd Alkhalik [1 ]
Gobran, Mai Ahmed [3 ]
Alqahtani, Saad Misfer [4 ]
Assiri, Abdullah M. [5 ]
Alqahtani, Saeed [5 ]
Alduraibi, Sharifa Khalid [6 ]
Aboualkheir, Mervat [7 ]
Almushayti, Ziyad A. [6 ]
Aldhilan, Asim S. [6 ]
Aly, Sameh Abdelaziz [8 ]
Alshamy, Asmaa A. [1 ]
机构
[1] Zagazig Univ, Fac Human Med, Dept Diagnost Radiol, Zagazig 44519, Egypt
[2] Najran Univ, Med Coll, Dept Internal Med, Div Radiol, Najran 61441, Saudi Arabia
[3] Zagazig Univ, Fac Human Med, Dept Surg Pathol, Zagazig 44519, Egypt
[4] Najran Univ, Najran Univ Hosp, Coll Med, Dept Pathol, Najran 61441, Saudi Arabia
[5] Najran Univ, Coll Med, Dept Surg, Najran 61441, Saudi Arabia
[6] Qassim Univ, Coll Med, Dept Radiol, Buraydah 52571, Saudi Arabia
[7] Taibah Univ, Coll Med, Dept Radiol & Med Imaging, Madinah 42353, Saudi Arabia
[8] Benha Univ, Fac Human Med, Dept Diagnost Radiol, Banha 13511, Egypt
关键词
MRI; mucormycosis; sinus; orbit; COVID-19; COMPUTED-TOMOGRAPHY;
D O I
10.3390/diagnostics13091546
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
There has been a notable increase in rhino-orbito-cerebral mucormycosis (ROCM) post-coronavirus disease 2019 (COVID-19), which is an invasive fungal infection with a fatal outcome. Magnetic resonance imaging (MRI) is a valuable tool for early diagnosis of ROCM and assists in the proper management of these cases. This study aimed to describe the characteristic MRI findings of ROCM in post-COVID-19 patients to help in the early diagnosis and management of these patients. This retrospective descriptive study was conducted at a single hospital and included 52 patients with COVID-19 and a histopathologically proven ROCM infection who were referred for an MRI of the paranasal sinuses (PNS) due to sino-orbital manifestations. Two radiologists reviewed all the MR images in consensus. The diagnosis was confirmed by histopathological examination. The maxillary sinus was the most commonly affected PNS (96.2%). In most patients (57.7%), multiple sinuses were involved with the black turbinate sign on postcontrast images. Extrasinus was evident in 43 patients with orbital involvement. The pterygopalatine fossa was involved in four patients. Three patients had cavernous sinus extension, two had pachymeningeal enhancement, and one had epidural collection. The alveolar margin was affected in two patients, and five patients had an extension to the cheek. The awareness of radiologists by the characteristic MRI features of ROCM in post-COVID-19 patients helps in early detection, early proper management, and prevention of morbid complications.
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页数:11
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