Cost Effective Electrochemical Sensor for L-Methionine Based on Graphitic Carbon Nitride Sheets Modified Electrode

被引:2
作者
Ajith, Ajay [1 ]
John, S. Abraham [1 ]
机构
[1] Gandhigram Rural Inst, Ctr Nanosci & Nanotechnol, Dept Chem, Dindigul 624302, Tamilnadu, India
关键词
Graphitic carbon nitride nanosheets; Melamine; Differential pulse voltammetry; L-Methionine; Human blood serum; GOLD NANOPARTICLES; COLORIMETRIC DETECTION; NANOSHEETS; OXIDATION; FILM; FABRICATION; PLASMA; ACID;
D O I
10.1002/elan.202200063
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
L-methionine (L-Me) deficiency in human body leads to several complications. In the present work, graphitic carbon nitride nanosheets (GCN-S) modified glassy carbon electrode (GC/GCN-S) was developed as a cost effective electrochemical sensor for L-Me. The oxidation of L-Me at bare GC electrode shows an ill-defined peak and it was unstable whereas a well-defined stable oxidation peak was obtained at GC/GCN-S electrode. While increasing L-Me concentration from 100 nM to 0.2 mM, the amperometric current increases linearly with R-2=0.9901 and LOD was found to be 0.32 nM (S/N=3). Finally, GC/GCN-S electrode was used to determine L-Me in blood serum samples.
引用
收藏
页数:8
相关论文
共 40 条
[1]   Colloidal-gold cysteamine-modified carbon paste electrodes as suitable electrode materials for the electrochemical determination of sulphur-containing compounds -: Application to the determination of methionine [J].
Agüí, L ;
Manso, J ;
Yáñez-Sedeño, P ;
Pingarrón, JM .
TALANTA, 2004, 64 (04) :1041-1047
[2]  
Bhatia P., 2020, INT J NEUROSCI, V11, P1
[3]   Synthesis of Pt doped TiO2 nanoparticles: Characterization and application for electrocatalytic oxidation of L-methionine [J].
Chekin, Fereshteh ;
Bagheri, Samira ;
Abd Hamid, Sharifah Bee .
SENSORS AND ACTUATORS B-CHEMICAL, 2013, 177 :898-903
[4]   Carbon electrodes modified with ruthenium metallodendrimer multilayers for the mediated oxidation of methionine and insulin at physiological pH [J].
Cheng, L ;
Pacey, GE ;
Cox, JA .
ANALYTICAL CHEMISTRY, 2001, 73 (22) :5607-5610
[5]   FLOW-INJECTION DETERMINATION OF METHIONINE WITH AMPEROMETRIC DETECTION AT A STABLE MODIFIED ELECTRODE [J].
COX, JA ;
DABEKZLOTORZYNSKA, E .
ELECTROANALYSIS, 1991, 3 (03) :239-242
[6]   Recent development in exfoliated two-dimensional g-C3N4 nanosheets for photocatalytic applications [J].
Dong, Xiaoping ;
Cheng, Fuxing .
JOURNAL OF MATERIALS CHEMISTRY A, 2015, 3 (47) :23642-23652
[7]   L-methionine reduces oxidant stress in endothelial cells:: Role of heme oxygenase-1, ferritin, and nitric oxide [J].
Erdmann, K ;
Grosser, N ;
Schröder, H .
AAPS JOURNAL, 2005, 7 (01) :E195-E200
[8]   Determination of free methionine in human blood plasma by species-specific isotope dilution HPLC-ICP-MS using 34S-labelled methionine [J].
Galilea San Blas, Oscar ;
Moreno Sanz, F. ;
Herrero Espilez, P. ;
Prieto Garcia, Belen ;
Alvarez Menendez, Francisco V. ;
Manuel Marchante-Gayon, Juan ;
Garcia Alonso, Jose Ignacio .
JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY, 2016, 31 (09) :1885-1894
[9]  
Ganesh K., 2020, DIAM RELAT MATER, V108
[10]   Toxicity of methionine in humans [J].
Garlick, Peter J. .
JOURNAL OF NUTRITION, 2006, 136 (06) :1722S-1725S