Visual Performance and Binocular/Accommodative Function of STOP Contact Lenses Compared With MiSight

Objectives:The objective of this study was to compare the visual performance and binocular/accommodative function of two novel S.T.O.P. design (F2 and DT) contact lenses against MiSight when worn by myopic, young adults.Method:This was a prospective, randomized, cross-over, single-masked study. Each lens was worn daily wear with overnight peroxide disinfection for approximately 7 days. Visual performance was assessed with subjective ratings (0-100): clarity of vision and lack of ghosting (far away, intermediate, and near), vision when driving, overall vision satisfaction, and with monocular high-contrast and low-contrast visual acuity (HCVA/LCVA) at 6 m, binocular HCVA (6 m, 70 cm, 50 cm, and 40 cm), binocular LCVA (6 m and 70 cm). Binocular function was assessed with heterophorias (3 m and 40 cm). Accommodative function was assessed with monocular accommodative facility (AF: 40 cm) and dynamic monocular accommodative response (AR: 6 m, 70 cm, and 40 cm).Results:F2 was rated higher than MiSight for clarity of vision (near and intermediate) and lack-of-ghosting (P<0.001), while MiSight was rated higher than DT for clarity of vision (near, P<0.001). MiSight was better than F2 and DT for monocular HCVA (6 m) and binocular HCVA (6 m and 40 cm, P <= 0.02), but the maximum difference was <= 2 letters. There were no differences between designs for heterophoria (P=0.61) nor were there any differences between DT and MiSight for any accommodative measure (P>0.1). F2 was higher for monocular-AF (P=0.007) and lower for AR (70 cm and 40 cm; P <= 0.007) compared with MiSight.Conclusions:The visual performance and binocular/accommodative function of S.T.O.P. designs F2 and DT were comparable with MiSight. F2 outperformed MiSight in some aspects of subjective visual performance and monocular accommodative function.