Harnessing Healing Power: A Comprehensive Review on Platelet-Rich Plasma in Compound Fracture Care

被引:3
作者
Kale, Prathamesh [1 ]
Shrivastava, Sandeep [1 ]
Pundkar, Aditya [2 ]
Balusani, Prashanth [3 ]
机构
[1] Datta Meghe Inst Med Sci, Jawaharlal Nehru Med Coll, Orthopaed Surg, Wardha, India
[2] Datta Meghe Inst Med Sci, Jawaharlal Nehru Med Coll, Orthopaed, Wardha, India
[3] Datta Meghe Inst Med Sci, Jawaharlal Nehru Med Coll, Orthopaed & Traumatol, Wardha, India
关键词
ethical considerations; inflammation reduction; soft tissue repair; bone healing; compound fractures; platelet-rich plasma (prp);
D O I
10.7759/cureus.52722
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This comprehensive review explores the applications of platelet -rich plasma (PRP) in the context of compound fracture care, providing a thorough examination of its biological mechanisms, preparation techniques, and clinical implications. The analysis highlights PRP's potential in accelerating bone healing, enhancing soft tissue repair, reducing inflammation and infection risks, and managing pain during fracture recovery. The review underscores the importance of ethical and regulatory considerations in integrating PRP into orthopaedic practice, emphasising informed consent, transparent patient communication, and ongoing monitoring of ethical concerns. Looking ahead, the implications for the future of compound fracture care suggest a transformative shift with the potential for personalised medicine approaches and emerging technologies. However, the conclusion calls for a balanced perspective, acknowledging the promising applications of PRP while emphasising the need for responsible and ethical use. The collaborative efforts of healthcare professionals, researchers, and regulatory bodies are crucial in navigating this evolving landscape and harnessing the healing power of PRP to redefine orthopaedic care for individuals with compound fractures.
引用
收藏
页数:8
相关论文
共 36 条
[21]   The Economics and Regulation of PRP in the Evolving Field of Orthopedic Biologics [J].
Jones I.A. ;
Togashi R.C. ;
Thomas Vangsness C., Jr .
Current Reviews in Musculoskeletal Medicine, 2018, 11 (4) :558-565
[22]   Clinical Effectiveness of Platelet-Rich Plasma for Long-Bone Delayed Union and Nonunion: A Systematic Review and Meta-Analysis [J].
Li, Shang ;
Xing, Fei ;
Luo, Rong ;
Liu, Ming .
FRONTIERS IN MEDICINE, 2022, 8
[23]   Ethics, Evidence Based Sports Medicine, and the Use of Platelet Rich Plasma in the English Premier League [J].
McNamee, M. J. ;
Coveney, C. M. ;
Faulkner, A. ;
Gabe, J. .
HEALTH CARE ANALYSIS, 2018, 26 (04) :344-361
[24]   Assessment, Quantification, and Management of Fracture Pain: from Animals to the Clinic [J].
McVeigh, Luke G. ;
Perugini, Anthony J. ;
Fehrenbacher, Jill C. ;
White, Fletcher A. ;
Kacena, Melissa A. .
CURRENT OSTEOPOROSIS REPORTS, 2020, 18 (05) :460-470
[25]  
Ong FS, 2012, EXPERT REV MOL DIAGN, V12, P593, DOI [10.1586/erm.12.59, 10.1586/ERM.12.59]
[26]  
Ramaswamy Reddy Shwetha Hulimavu, 2018, J Oral Maxillofac Pathol, V22, P367, DOI [10.4103/jomfp.jomfp_93_18, 10.4103/jomfp.JOMFP_93_18]
[27]  
Research, 2023, Can platelet rich plasma improve bone healing in patients with osteoarthritis or nonunion healing?
[28]   Process Optimization and Efficacy Assessment of Standardized PRP for Tendinopathies in Sports Medicine: Retrospective Study of Clinical Files and GMP Manufacturing Records in a Swiss University Hospital [J].
Sebbagh, Patrick ;
Hirt-Burri, Nathalie ;
Scaletta, Corinne ;
Abdel-Sayed, Philippe ;
Raffoul, Wassim ;
Gremeaux, Vincent ;
Laurent, Alexis ;
Applegate, Lee Ann ;
Gremion, Gerald .
BIOENGINEERING-BASEL, 2023, 10 (04)
[29]   Case Study Analysis as an Effective Teaching Strategy: Perceptions of Undergraduate Nursing Students From a Middle Eastern Country [J].
Seshan, Vidya ;
Matua, Gerald Amandu ;
Raghavan, Divya ;
Arulappan, Judie ;
Al Hashmi, Iman ;
Roach, Erna Judith ;
Sunderraj, Sheeba Elizebath ;
Prince, Emi John .
SAGE OPEN NURSING, 2021, 7
[30]  
Sheen JR, 2023, STATPEARLS