Harnessing Healing Power: A Comprehensive Review on Platelet-Rich Plasma in Compound Fracture Care

被引:3
作者
Kale, Prathamesh [1 ]
Shrivastava, Sandeep [1 ]
Pundkar, Aditya [2 ]
Balusani, Prashanth [3 ]
机构
[1] Datta Meghe Inst Med Sci, Jawaharlal Nehru Med Coll, Orthopaed Surg, Wardha, India
[2] Datta Meghe Inst Med Sci, Jawaharlal Nehru Med Coll, Orthopaed, Wardha, India
[3] Datta Meghe Inst Med Sci, Jawaharlal Nehru Med Coll, Orthopaed & Traumatol, Wardha, India
关键词
ethical considerations; inflammation reduction; soft tissue repair; bone healing; compound fractures; platelet-rich plasma (prp);
D O I
10.7759/cureus.52722
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
This comprehensive review explores the applications of platelet -rich plasma (PRP) in the context of compound fracture care, providing a thorough examination of its biological mechanisms, preparation techniques, and clinical implications. The analysis highlights PRP's potential in accelerating bone healing, enhancing soft tissue repair, reducing inflammation and infection risks, and managing pain during fracture recovery. The review underscores the importance of ethical and regulatory considerations in integrating PRP into orthopaedic practice, emphasising informed consent, transparent patient communication, and ongoing monitoring of ethical concerns. Looking ahead, the implications for the future of compound fracture care suggest a transformative shift with the potential for personalised medicine approaches and emerging technologies. However, the conclusion calls for a balanced perspective, acknowledging the promising applications of PRP while emphasising the need for responsible and ethical use. The collaborative efforts of healthcare professionals, researchers, and regulatory bodies are crucial in navigating this evolving landscape and harnessing the healing power of PRP to redefine orthopaedic care for individuals with compound fractures.
引用
收藏
页数:8
相关论文
共 36 条
[1]   The Use of Platelet-Rich Plasma (PRP) for the Management of Non-union Fractures [J].
Andersen, Christian ;
Wragg, Nicholas M. ;
Shariatzadeh, Maryam ;
Wilson, Samantha Louise .
CURRENT OSTEOPOROSIS REPORTS, 2021, 19 (01) :1-14
[2]  
[Anonymous], 2023, Potential Pros And Cons of PRP Injections
[3]  
[Anonymous], 2009, Screening Donated Blood for Transfusion-Transmissible Infections
[4]  
Recommendations
[5]  
[Anonymous], 2020, Advantages and Disadvantages of Hydrogen Energy | Boiler Guide
[6]  
[Anonymous], 2023, Regenerative Orthopedic Case of the Week-Stress Fracture with Osteonecrosis
[7]   Conservative Treatment of the Fifth Metatarsal Bone Fractures in Professional Football Players Using Platelet-Rich Plasma [J].
Bezuglov, Eduard ;
Zholinsky, Andrey ;
Chernov, Gleb ;
Khaitin, Vladimir ;
Goncharov, Evgeniy ;
Waskiewicz, Zbigniew ;
Barskova, Ekaterina ;
Lazarev, Artemii .
FOOT & ANKLE SPECIALIST, 2022, 15 (01) :62-66
[8]   Basic concepts regarding fracture healing and the current options and future directions in managing bone fractures [J].
Bigham-Sadegh, Amin ;
Oryan, Ahmad .
INTERNATIONAL WOUND JOURNAL, 2015, 12 (03) :238-247
[9]  
Bonnie RJ., 2019, PROMISE ADOLESCENCE, P37, DOI DOI 10.17226/25388
[10]   Platelet-Rich Plasma: The Choice of Activation Method Affects the Release of Bioactive Molecules [J].
Cavallo, Carola ;
Roffi, Alice ;
Grigolo, Brunella ;
Mariani, Erminia ;
Pratelli, Loredana ;
Merli, Giulia ;
Kon, Elizaveta ;
Marcacci, Maurilio ;
Filardo, Giuseppe .
BIOMED RESEARCH INTERNATIONAL, 2016, 2016