Two new ketene derivatives from the endophytic fungus Daldinia eschscholtzii J11

被引：1
作者：
Lu, Song-Mei [1 ,2 ,3 ]
Liao, Cheng-Juan [1 ,2 ,3 ]
Xu, Yuan [1 ,2 ,3 ]
Gui, Teng-Yuan [1 ,2 ,3 ]
Sui, He-Lin [1 ,2 ,3 ]
Zhou, Min [1 ,2 ,3 ]
机构：
[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss, Kunming 650031, Peoples R China
[2] Yunnan Minzu Univ, Minist Educ, Kunming 650031, Peoples R China
[3] Yunnan Minzu Univ, Sch Ethn Med, Kunming 650031, Peoples R China
来源：
PHYTOCHEMISTRY LETTERS | 2023年 / 58卷
基金：
中国国家自然科学基金;
关键词：
Daldinia eschscholtzii; Cyclopentenone derivative; Pyrone derivative; Antioxidant activity; Neuroprotective effect; Euphorbia pekinensis; POLYKETIDES;
D O I：
10.1016/j.phytol.2023.11.001
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new secondary metabolites, including a new cyclopentenone derivative (1) and a new pyrone derivative (2), together with seventeen known compounds (3-19), were isolated from the fermentation of the endophytic fungus Daldinia eschscholtzii J11 in the stems of Euphorbia pekinensis. Their structures were elucidated by using NMR and HRESIMS data and by comparing the information with literature data. Compounds 3, 4, and 18 possessed moderate ABTS+ radical scavenging activity, and Compound 12 exhibited a potential neuroprotective effect against 6-OHDA-induced injury in PC12 cells. In addition, all compounds were evaluated for their tyrosinase inhibitory activities.
引用
收藏
页码：81 / 85
页数：5
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