A Case Report of Refractory Diffuse Alveolar Hemorrhage as a Complication of Antiphospholipid Syndrome and Review of Its Management

被引：1

作者：

Ruzdija, Denis ^{[1
]}

Bertolo, Aaron ^{[1
]}

Pandya, Shaunak K. ^{[2
]}

Amaraneni, Akshay ^{[3
]}

机构：

[1] Univ Arizona, Internal Med, Tucson, AZ 85724 USA

[2] Univ Arizona, Hematol Oncol, Tucson, AZ USA

[3] Univ Arizona Canc Ctr, Hematol & Oncol, Tucson, AZ USA

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 10期

关键词：

immunosuppressive therapy; dah; aps; antiphospholipid syndrome; diffuse alveolar hemorrhage;

D O I：

10.7759/cureus.47267

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Diffuse alveolar hemorrhage is a rare complication of antiphospholipid syndrome with high mortality rates. Early diagnosis and treatment with steroids and immunosuppressive agents, along with the achievement of hemostasis and hemodynamic stability, is critical to improving outcomes. This case demonstrates the complexity of managing refractory diffuse alveolar hemorrhage in a 48-year-old woman with antiphospholipid syndrome requiring treatment with high-dose corticosteroids, rituximab, and cyclophosphamide.

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页数：5

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