Adult Gene Therapy for Epilepsy in a Model of Angelman Syndrome: Hope or Hype?

被引:0
作者
Huguenard, John R. [1 ]
机构
[1] Stanford Univ, Sch Med, Neurol & Neurol Sci, Stanford, CA 94305 USA
关键词
PHENOTYPES; MUTATIONS;
D O I
10.1177/15357597231191885
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
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页码:312 / 314
页数:3
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  • [1] [Anonymous], SFARI TAG ANGELMAN S
  • [2] Angelman syndrome: a review of the clinical and genetic aspects
    Clayton-Smith, J
    Laan, L
    [J]. JOURNAL OF MEDICAL GENETICS, 2003, 40 (02) : 87 - 95
  • [3] GABA and epileptogenesis: comparing gabrb3 gene-deficient mice with Angelman syndrome in man
    DeLorey, TM
    Olsen, RW
    [J]. EPILEPSY RESEARCH, 1999, 36 (2-3) : 123 - 132
  • [4] Epilepsy in patients with Angelman syndrome
    Fiumara, Agata
    Pittala, Annarita
    Cocuzza, Mariadonatella
    Sorge, Giovanni
    [J]. ITALIAN JOURNAL OF PEDIATRICS, 2010, 36 : 31
  • [5] Electrophysiological Phenotype in Angelman Syndrome Differs Between Genotypes
    Frohlich, Joel
    Miller, Meghan T.
    Bird, Lynne M.
    Garces, Pilar
    Purtell, Hannah
    Hoener, Marius C.
    Philpot, Benjamin D.
    Sidorov, Michael S.
    Tan, Wen-Hann
    Hernandez, Maria-Clemencia
    Rotenberg, Alexander
    Jeste, Shafali S.
    Krishnan, Michelle
    Khwaja, Omar
    Hipp, Joerg F.
    [J]. BIOLOGICAL PSYCHIATRY, 2019, 85 (09) : 752 - 759
  • [6] Altered Ultrasonic Vocalization and Impaired Learning and Memory in Angelman Syndrome Mouse Model with a Large Maternal Deletion from Ube3a to Gabrb3
    Jiang, Yong-hui
    Pan, Yanzhen
    Zhu, Li
    Landa, Luis
    Yoo, Jong
    Spencer, Corinne
    Lorenzo, Isabel
    Brilliant, Murray
    Noebels, Jeffrey
    Beaudet, Arthur L.
    [J]. PLOS ONE, 2010, 5 (08):
  • [7] UBE3A/E6-AP mutations cause Angelman syndrome
    Kishino, T
    Lalande, M
    Wagstaff, J
    [J]. NATURE GENETICS, 1997, 15 (01) : 70 - 73
  • [8] Lalande M, 1999, Adv Neurol, V79, P421
  • [9] Antisense oligonucleotide therapy rescues disturbed brain rhythms and sleep in juvenile and adult mouse models of Angelman syndrome
    Lee, Dongwon
    Chen, Wu
    Kaku, Heet Naresh
    Zhuo, Xinming
    Chao, Eugene S.
    Soriano, Armand
    Kuncheria, Allen
    Flores, Stephanie
    Kim, Joo Hyun
    Rivera, Armando
    Rigo, Frank
    Jafar-nejad, Paymaan
    Beaudet, Arthur L.
    Caudill, Matthew S.
    Xue, Mingshan
    [J]. ELIFE, 2023, 12
  • [10] Distinct phenotypes distinguish the molecular classes of Angelman syndrome
    Lossie, AC
    Whitney, MM
    Amidon, D
    Dong, HJ
    Chen, P
    Theriaque, D
    Hutson, A
    Nicholls, RD
    Zori, RT
    Williams, CA
    Driscoll, DJ
    [J]. JOURNAL OF MEDICAL GENETICS, 2001, 38 (12) : 834 - 845