Limbic encephalitis associated with inappropriate secretion of antidiuretic hormone. A case report and literature review

被引:0
作者
Orellano, Pablo [1 ]
Ramos, Abayuba Perna [2 ]
机构
[1] Hosp Reg Mercedes, Med Internista, Montevideo, Uruguay
[2] Hosp Clin Montevideo, Fac Med, Inst Neurol, Montevideo, Uruguay
来源
REVISTA MEDICA DEL URUGUAY | 2023年 / 39卷 / 01期
关键词
Limbic; Hyponatremia; Inappropriate ADH syndrome; Dementia; AUTOIMMUNE; ANTI-LGI1; DEMENTIA;
D O I
10.29193/RMU.39.1.10
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Autoimmune limbic encephalitis is a rather unusual neu-rological condition with subacute progression and neu-ropsychological symptoms. Currently, acute or mainte-nance treatment with immunotherapy is targeted depen-ding on the accompanying neural specific antibody and the presence or absence of cancer.The study presents the case of a 52-year-old woman suffering from autoimmune hypothyroidism, syndrome of inappropriate secretion of anti-diuretic hormone (SIADH) and persistent hyponatremia, with progressive evolution which involved memory loss and faciobrachial dystonic seizures (FBDS). She was timely diagnosed with limbic encephalitis and was treated with intravenous combined corticosteroids and immunoglobulin therapy. Response was good, with minimum neuropsychological.Recognizing this condition allows for early diagnosis and treatment, what is key to improve the prognosis of these patients.
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页数:8
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