Safety and efficacy of a feed additive consisting of an essential oil from the leaves of Laurus nobilis L. (laurel leaf oil) for all animal species (FEFANA asbl)

被引:13
|
作者
Bampidis, Vasileios
Bampidis, Vasileios
Azimonti, Giovanna
Bastos, Maria de Lourdes
Christensen, Henrik
Durjava, Mojca
Kouba, Maryline
Lopez-Alonso, Marta
Puente, Secundino Lopez
Marcon, Francesca
Mayo, Baltasar
Pechova, Alena
Petkova, Mariana
Ramos, Fernando
Sanz, Yolanda
Villa, Roberto Edoardo
Woutersen, Ruud
Brantom, Paul
Chesson, Andrew
Schlatter, Josef
Schrenk, Dieter
Westendorf, Johannes
Manini, Paola
Pizzo, Fabiola
Dusemund, Birgit
机构
关键词
sensory additives; flavouring compounds; Laurus nobilis L; laurel leaf oil; methyleugenol; estragole; elemicin; NATURALLY-OCCURRING ALKENYLBENZENES; UNSCHEDULED DNA-SYNTHESIS; POST-LABELING ANALYSIS; ADDUCTS; RAT; METHYLEUGENOL; GENOTOXICITY; SAFROLE; ESTRAGOLE; MODELS;
D O I
10.2903/j.efsa.2023.7875
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of an essential oil from the leaves of Laurus nobilis L. (laurel leaf oil), when used as a sensory additive for all animal species. The additive contains up to 4% methyleugenol. The use of the additive at 2 mg/kg complete feed in dogs and cats was considered of low concern. For other long-living and reproductive animals, the use of the additive at 10 mg/kg was considered of concern. For short-living animals, the Panel had no safety concern when the additive is used at 10 mg/kg complete feed for turkeys for fattening, piglets and other growing Suidae, pigs for fattening, veal calves (milk replacer), cattle for fattening and other growing ruminants, horses and rabbits for meat production, salmonids and other fin fish; and at 8.5 mg/kg for chickens for fattening, other growing poultry and other minor species for fattening. The use of laurel leaf oil up to the highest level in feed which was considered of no concern for target animals was also expected to be of no concern for consumers. The additive should be considered as irritant to skin and eyes and the respiratory tract. Due to the high concentration of methyleugenol (>= 1%), the additive was classified by the applicant as suspected of causing genetic defects and of causing cancer and should be handled accordingly. The use of the additive under the proposed conditions of use was not expected to pose a risk for the environment. Since the leaves of L. nobilis and their preparations were recognised to flavour food and their function in feed would be the same, no further demonstration of efficacy was considered necessary.
引用
收藏
页数:28
相关论文
共 50 条
  • [41] Safety and efficacy of feed additives consisting of expressed sweet orange peel oil and its fractions from Citrus sinensis (L.) Osbeck for use in all animal species (FEFANA asbl)
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Durjava, Mojca Fasmon
    Kouba, Maryline
    Lopez-Alonso, Marta
    Puente, Secundino Lopez
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Sanz, Yolanda
    Villa, Roberto Edoardo
    Woutersen, Ruud
    Brantom, Paul
    Chesson, Andrew
    Westendorf, Johannes
    Manini, Paola
    Pizzo, Fabiola
    Dusemund, Birgit
    EFSA JOURNAL, 2021, 19 (11)
  • [42] Safety and efficacy of a feed additive consisting of a tincture derived from the flowers of Syzygium aromaticum (L.) Merr. & LM Perry (clove tincture) for all animal species (FEFANA asbl)
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Dusemund, Birgit
    Durjava, Mojca
    Kouba, Maryline
    Lopez-Alonso, Marta
    Puente, Secundino Lopez
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Villa, Roberto Edoardo
    Woutersen, Ruud
    Brantom, Paul
    Chesson, Andrew
    Schlatter, Josef
    Westendorf, Johannes
    Dirven, Yvette
    Manini, Paola
    EFSA JOURNAL, 2024, 22 (05)
  • [43] Safety and efficacy of feed additives consisting of expressed lemon oil and its fractions from Citrus limon (L.) Osbeck and of lime oil from Citrus aurantiifolia (Christm.) Swingle for use in all animal species (FEFANA asbl)
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Kouba, Maryline
    Durjava, Mojca Fasmon
    Lopez-Alonso, Marta
    Lopez Puente, Secundino
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Sanz, Yolanda
    Villa, Roberto Edoardo
    Woutersen, Ruud
    Brantom, Paul
    Chesson, Andrew
    Westendorf, Johannes
    Galobart, Jaume
    Manini, Paola
    Pizzo, Fabiola
    Dusemund, Birgit
    EFSA JOURNAL, 2021, 19 (04)
  • [44] Ultrasound-assisted emulsion of laurel leaves essential oil (Laurus nobilis L.) encapsulated by SFEE
    Lima Reis, Paulia M. C.
    Mezzomo, Natalia
    Aguiar, Gean Pablo S.
    Teixeira Lemos Senna, Elenara Maria
    Hense, Haiko
    Ferreira, Sandra R. S.
    JOURNAL OF SUPERCRITICAL FLUIDS, 2019, 147 : 284 - 292
  • [45] OIL CONTAINING TISSUE, THE ESSENTIAL OIL CONTENTS AND THE CHEMICAL COMPOSITION OF ESSENTIAL OIL IN LAUREL LEAF (LAURUS-NOBILIS L)
    YOSHIDA, T
    JAPANESE JOURNAL OF TROPICAL AGRICULTURE, 1979, 23 (01): : 6 - 10
  • [46] Safety and efficacy of a feed additive consisting of a tincture from the bark of Cinnamomum verum J. Presl (cinnamon tincture) for use in all animal species (FEFANA asbl)
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Durjava, Mojca Fasmon
    Kouba, Maryline
    Lopez-Alonso, Marta
    Puente, Secundino Lopez
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Sanz, Yolanda
    Villa, Roberto Edoardo
    Woutersen, Ruud
    Brantom, Paul
    Chesson, Andrew
    Westendorf, Johannes
    Manini, Paola
    Pizzo, Fabiola
    Dusemund, Birgit
    EFSA JOURNAL, 2021, 19 (12)
  • [47] Safety and efficacy of an essential oil from Elettaria cardamomum (L.) Maton when used as a sensory additive in feed for all animal species
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Kouba, Maryline
    Durjava, Mojca Kos
    Lopez-Alonso, Marta
    Puente, Secundino Lopez
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Sanz, Yolanda
    Villa, Roberto
    Woutersen, Ruud
    Brantom, Paul
    Chesson, Andrew
    Kolar, Boris
    Van Beelen, Patrick
    Westendorf, Johannes
    Gregoretti, Lucilla
    Manini, Paola
    Dusemund, Birgit
    EFSA JOURNAL, 2019, 17 (06)
  • [48] Safety of a feed additive consisting of propyl gallate for all animal species (FEFANA ABL)
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Durjava, Mojca
    Dusemund, Birgit
    Kouba, Maryline
    Lopez-Alonso, Marta
    Puente, Secundino Lopez
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Villa, Roberto Edoardo
    Woutersen, Ruud
    Galobart, Jaume
    Innocenti, Matteo
    Bories, Georges
    Gropp, Juergen
    EFSA JOURNAL, 2024, 22 (02)
  • [49] Comparative study on the chemical composition of laurel (Laurus nobilis L.) leaves from Greece and Georgia and the antibacterial activity of their essential oil
    Stefanova, Galina
    Girova, Tanya
    Gochev, Velizar
    Stoyanova, Magdalena
    Petkova, Zhana
    Stoyanova, Albena
    Zheljazkov, Valtcho D.
    HELIYON, 2020, 6 (12)
  • [50] Safety and efficacy of a feed additive consisting of a flavonoid-rich dried extract of Citrus x aurantium L. fruit (bitter orange extract) for use in all animal species (FEFANA asbl)
    Bampidis, Vasileios
    Azimonti, Giovanna
    Bastos, Maria de Lourdes
    Christensen, Henrik
    Durjava, Mojca Fasmon
    Kouba, Maryline
    Lopez-Alonso, Marta
    Puente, Secundino Lopez
    Marcon, Francesca
    Mayo, Baltasar
    Pechova, Alena
    Petkova, Mariana
    Ramos, Fernando
    Sanz, Yolanda
    Villa, Roberto Edoardo
    Woutersen, Ruud
    Brantom, Paul
    Chesson, Andrew
    Westendorf, Johannes
    Manini, Paola
    Pizzo, Fabiola
    Dusemund, Birgit
    EFSA JOURNAL, 2021, 19 (07)