Do omega-3 fatty acids increase risk of atrial fibrillation?

被引：7

作者：

Bork, Christian S. ^{[1
]}

Myhre, Peder L. ^{[2
,3
]}

Schmidt, Erik B. ^{[4
,5
]}

机构：

[1] Aalborg Univ Hosp, Dept Cardiol, Aalborg, Denmark

[2] Univ Oslo, Inst Clin Med, KG Jebsen Ctr Cardiac Biomarkers, Oslo, Norway

[3] Akershus Univ Hosp, Dept Cardiol, Div Med, Lorenskog, Norway

[4] Aalborg Univ, Dept Clin Med, Aalborg, Denmark

[5] Forskningenshus Hus, Soendre Skovvej 15, DK-9000 Aalborg, Denmark

来源：

CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE | 2023年 / 26卷 / 02期

关键词：

atrial fibrillation; marine omega-3 fatty acid supplements; omega-3 fatty acids; FATTY-ACIDS; FISH-OIL; SUPPLEMENTATION; DISEASE;

D O I：

10.1097/MCO.0000000000000907

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Purpose of the reviewTo summarize the findings from recent observational follow-up studies and randomized trials of plant- and marine omega-3 fatty acids on the risk of atrial fibrillation (AF).Recent findingsRecent randomized cardiovascular outcome trials have indicated that supplements with marine omega-3 fatty acids may be associated with a higher risk of AF, and a meta-analysis has suggested that marine omega-3 fatty acid supplements were associated with a 25% higher relative risk of AF. Also, a recent large observational study reported a modest higher risk of AF in habitual users of marine omega-3 fatty acid supplements. However, recent observational biomarker studies of circulating and adipose tissue content of marine omega-3 fatty acids have in contrast reported a lower risk of AF. Very limited knowledge exists on the role of plant-derived omega-3 fatty acids and AF.Marine omega-3 fatty acid supplements may increase the risk of AF, whereas biomarkers reflecting consumption of marine omega-3 fatty acids have been linked to a lower risk of AF. Clinicians should inform patients that marine omega-3 fatty acid supplement may increase AF risk, and this should be taking into account when discussing pros and cons of taking supplements with marine omega-3 fatty acids.

引用

页码：78 / 82

页数：5

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