Prevalence, Severity, and Description of Dental Anomalies in Children Treated for Acute Lymphoblastic Leukemia

被引：0

作者：

Boutin, Cynthia

Huynh, Nelly ^{[1
]}

Rompre, Pierre ^{[2
]}

Laverdiere, Caroline ^{[3
]}

Asselin, Marie-Eve ^{[4
]}

机构：

[1] Univ Montreal, Montreal, PQ, Canada

[2] Univ Montreal, Fac Dent, Montreal, PQ, Canada

[3] Univ Montreal, Div Hematol & Oncol, Ctr Hosp Univ St Justine, Montreal, PQ, Canada

[4] Univ Montreal, Div Dent, Montreal, PQ, Canada

来源：

PEDIATRIC DENTISTRY | 2023年 / 45卷 / 06期

关键词：

ACUTE LYMPHOBLASTIC LEUKEMIA; DENTAL ANOMALIES; LONG-TERM SURVIVORS; COLI L-ASPARAGINASE; CHILDHOOD; ABNORMALITIES; CHEMOTHERAPY;

D O I：

暂无

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

To assess the prevalence and severity of and describe dental anomalies in children treated for acute lymphoblastic leukemia (ALL) under recent Dana-Farber Cancer Institute (DFCI) protocols. Methods: Patients aged between 14 and 25 years old having received a diag-nosis of ALL before the age of 11 years and after September 2000 received clinical and radiographic oral examinations. Results: Dental anomalies were observed in 26 (51.0 percent) of 51 subjects. Microdontia was the most prevalent dental defect (39.2 percent). Impacted permanent second molars were observed in five (9.8 percent) patients. Being age five years or younger at diagnosis significantly increased the prevalence and severity of dental anomalies (P<0.001). Conclusions: Recent DFCI protocols showed a decreased prevalence of dental disturbances. The anoma-lies observed may still alter the development of the dental arches and occlusion in pediatric ALL survivors. Further research is needed to confirm the association between ALL treatment and permanent second molar impaction. (Pediatr Dent 2023;45(6):465-8) Received February 11, 2023 Last Revision August 19, 2023 | Accepted August 22, 2023

引用

页码：465 / 468

页数：4

共 22 条

[1] Prevalence of ectopic eruption, impaction, retention and agenesis of the permanent second molar [J].