Anal Carcinoma, Version 2.2023

被引:48
作者
Benson III, Al B. [1 ]
Venook, Alan P. [2 ]
Al-Hawary, Mahmoud M. [3 ]
Azad, Nilofer [4 ]
Chen, Yi-Jen [5 ]
Ciombor, Kristen K. [6 ]
Cohen, Stacey [7 ]
Cooper, Harry S. [8 ]
Deming, Dustin [9 ]
Garrido-Laguna, Ignacio [10 ]
Grem, Jean L. [11 ]
Hecht, J. Randolph [12 ]
Hoffe, Sarah [13 ]
Hubbard, Joleen [14 ]
Hunt, Steven [15 ,16 ]
Hussan, Hisham [17 ]
Jeck, William [18 ]
Johung, Kimberly L. [19 ]
Joseph, Nora
Kirilcuk, Natalie [20 ]
Krishnamurthi, Smitha [21 ,22 ]
Maratt, Jennifer [23 ]
Messersmith, Wells A. [24 ]
Meyerhardt, Jeffrey [25 ]
Miller, Eric D. [26 ,27 ]
Mulcahy, Mary F.
Nurkin, Steven [28 ]
Overman, Michael J. [29 ]
Parikh, Aparna [30 ]
Patel, Hitendra [31 ]
Pedersen, Katrina
Saltz, Leonard
Schneider, Charles [33 ]
Shibata, David [34 ]
Skibber, John M.
Sofocleous, Constantinos T. [32 ]
Stotsky-Himelfarb, Eden
Tavakkoli, Anna [35 ]
Willett, Christopher G.
Williams, Grant [36 ]
Algieri, Frankie [37 ]
Gurski, Lisa [37 ]
Stehman, Katie [37 ]
机构
[1] Northwestern Univ, Robert H Lurie Comprehens Canc Ctr, Evanston, IL 60208 USA
[2] UCSF Helen Diller Family Comprehens Canc Ctr, San Francisco, CA USA
[3] Univ Michigan, Rogel Canc Ctr, Ann Arbor, MI USA
[4] Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA
[5] City Hope Natl Med Ctr, Duarte, CA USA
[6] Vanderbilt Ingram Canc Ctr, Nashville, TN USA
[7] Fred Hutchinson Canc Ctr, Seattle, WA USA
[8] Fox Chase Canc Ctr, Philadelphia, PA USA
[9] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA
[10] Univ Utah, Huntsman Canc Inst, Salt Lake City, UT USA
[11] Fred & Pamela Buffett Canc Ctr, Omaha, NE USA
[12] UCLA Jonsson Comprehens Canc Ctr, Los Angeles, CA USA
[13] H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL USA
[14] Mayo Clin, Canc Ctr, Rochester, MN USA
[15] Barnes Jewish Hosp, Siteman Canc Ctr, St Louis, MO USA
[16] Washington Univ, Sch Med, St Louis, MO USA
[17] Univ Calif Davis, Comprehens Canc Ctr, Davis, CA USA
[18] Duke Canc Inst, Durham, NC USA
[19] Smilow Canc Hosp, Yale Canc Ctr, New Haven, CT USA
[20] Stanford Canc Inst, Stanford, CA USA
[21] Univ Hosp Seidman Canc Ctr, Case Comprehens Canc Ctr, Cleveland, OH USA
[22] Cleveland Clin, Taussig Canc Inst, Cleveland, OH USA
[23] Indiana Univ, Melvin & Bren Simon Comprehens Canc Ctr, Bloomington, IN USA
[24] Univ Colorado, Canc Ctr, Aurora, CO USA
[25] Dana Farber Brigham & Womens Canc Ctr, Boston, MA USA
[26] Ohio State Univ, James Canc Hosp, Comprehens Canc Ctr, Columbus, OH USA
[27] Solove Res Inst, Columbus, OH USA
[28] Roswell Park Comprehens Canc Ctr, Buffalo, NY USA
[29] Univ Texas MD Anderson Canc Ctr, Houston, TX USA
[30] Massachusetts Gen Hosp, Canc Ctr, Boston, MA USA
[31] Mem Sloan Kettering Canc Ctr, New York, NY USA
[32] Univ Calif San Diego, Moores Canc Ctr, San Diego, CA USA
[33] Univ Penn, Abramson Canc Ctr, Philadelphia, PA USA
[34] Univ Tennessee, Hlth Sci Ctr, Knoxville, TN USA
[35] UT Southwestern Simmons Comprehens Canc Ctr, Dallas, TX USA
[36] UAB, ONeal Comprehens Canc Ctr, Birmingham, AL USA
[37] Natl Comprehens Canc Network, Plymouth Meeting, PA USA
来源
JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2023年 / 21卷 / 06期
关键词
SQUAMOUS-CELL CARCINOMA; MODULATED RADIATION-THERAPY; HUMAN-PAPILLOMAVIRUS VACCINATION; CLINICAL-PRACTICE GUIDELINES; LONG-TERM OUTCOMES; HIV-POSITIVE MEN; QUALITY-OF-LIFE; SALVAGE ABDOMINOPERINEAL RESECTION; CETUXIMAB PLUS CHEMORADIOTHERAPY; SIMULTANEOUS INTEGRATED BOOST;
D O I
10.6004/jnccn.2023.0030
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
This discussion summarizes the NCCN Clinical Practice Guidelines for managing squamous cell anal carcinoma, which represents the most common histologic form of the disease. A multidisciplinary approach in-cluding physicians from gastroenterology, medical oncology, surgical oncology, radiation oncology, and radiology is necessary. Primary treat-ment of perianal cancer and anal canal cancer are similar and include chemoradiation in most cases. Follow-up clinical evaluations are rec-ommended for all patients with anal carcinoma because additional curative-intent treatment is possible. Biopsy-proven evidence of locally recurrent or persistent disease after primary treatment may require sur-gical treatment. Systemic therapy is generally recommended for extrap-elvic metastatic disease. Recent updates to the NCCN Guidelines for Anal Carcinoma include staging classification updates based on the 9th edition of the AJCC Staging System and updates to the systemic ther-apy recommendations based on new data that better define optimal treatment of patients with metastatic anal carcinoma.
引用
收藏
页码:653 / +
页数:25
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