The effectiveness of moisturizer on acute radiation-induced dermatitis in breast cancer patients: a systematic review and meta-analysis (Oct, 10.1007/s12282-022-01403-8, 2022)

被引：0

作者：

Sekiguchi, Kenji ^{[1
,2
]}

Sumi, Minako ^{[3
]}

Saito, Anneyuko ^{[4
]}

Zenda, Sadamoto ^{[5
]}

Arahira, Satoko ^{[6
]}

Iino, Keiko ^{[7
]}

Okumura, Masayuki ^{[8
]}

Kawai, Fujimi ^{[9
]}

Nozawa, Keiko ^{[10
]}

机构：

[1] Sonodakai Radiat Oncol Clin, 3-4-19 Hokima,Adachi Ku, Tokyo 1210064, Japan

[2] St Lukes Int Hosp, Dept Radiat Oncol, 9-1 Akashi Cho,Chuo Ku, Tokyo 1048560, Japan

[3] Metropolitan Geriatr Hosp, Radiat Oncol Dept, 35-2 Sakae Cho,Itabashi Ku, Tokyo 1730015, Japan

[4] Juntendo Univ, Dept Radiat Oncol, Fac Med, 2-1-1 Tomioka, Urayasu, Tokyo 2790021, Japan

[5] Natl Canc Ctr Hosp East, Dept Radiat Oncol, 6-5-1 Kashiwanoha, Kashiwa, Chiba 2778577, Japan

[6] Kanto Rosai Hosp, Div Radiat Oncol, 1-1 Kizukisumiyoshi Cho,Nakahara Ku, Kawasaki, Kanagawa 2118510, Japan

[7] Natl Coll Nursing, 1-2-1 Umezono, Kiyose, Tokyo 2048575, Japan

[8] Nagoya Univ Hosp, Dept Radiol, 65 Tsurumai Cho,Showa Ku, Nagoya 4668560, Japan

[9] St Lukes Int Univ, Library, Ctr Acad Resources, Tokyo 1040044, Japan

[10] Mejiro Univ, Fac Nursing, 320 Ukiya,Iwatsuki Ku, Saitama, Saitama 3398501, Japan

来源：

BREAST CANCER | 2023年 / 30卷 / 01期

关键词：

Acute radiation dermatitis; Breast cancer; Moisturizer; QOL;

D O I：

10.1007/s12282-022-01416-3

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: We conducted a systematic review and meta-analysis to investigate the effectiveness of moisturizers on acute radiation dermatitis (ARD) in breast cancer patients receiving radiotherapy (RT). Methods: PubMed, the Cochrane Library, CINAHL, and Ichushi-Web were searched for randomized controlled trials (RCTs) from April 2015 to March 2020. Assessments included type of intervention, cohort, outcomes, and quality of evidence. To evaluate the effect of moisturizer on ARD, we restricted analyses to studies comparing with standard skin care or no treatment. Outcomes were ARD severity and skin-related QOL (quality of life). Eligible studies were identified, and risk ratios and mean differences were extracted to compare outcome data. Results: We screened 210 RCTs along with 14 studies included in a previous iteration of this analysis (2016), supplemented by a hand search (n = 9). Finally, we included 6 RCTs that investigated the effectiveness of standard type moisturizers in breast cancer patients receiving RT. Evidence (weak certainty) suggests that moisturizer use might reduce ≥ grade 3 ARD. QOL assessed by Skindex-16 improved with moisturizer use. Pain and pruritus measured by the visual analog scale (VAS) resulted in a smaller and nonsignificant difference in favor of moisturizer use. However, the certainty of the evidence was very weak in QOL. Conclusions: The proactive use of moisturizer may play a role in reducing ARD and improving skin-related QOL, although the certainty of the evidence was weak to very weak. Future high-quality RCTs should be initiated to strengthen these results. © 2022, The Author(s), under exclusive licence to The Japanese Breast Cancer Society.

引用

页码：13 / 13

页数：1