Vaccination against HBV and HAV as Mode of Hepatitis Prevention among People Living with HIV-Data from ECEE Network Group

被引：5

作者：

Aimla, Kerstin ^{[1
]}

Kowalska, Justyna Dominika ^{[2
]}

Matulionyte, Raimonda ^{[3
]}

Mulabdic, Velida ^{[4
]}

Vassilenko, Anna ^{[5
]}

Bolokadze, Natalie ^{[6
]}

Jilich, David ^{[7
,8
]}

Antoniak, Sergii ^{[9
]}

Oprea, Cristiana ^{[10
]}

Balayan, Tatevik ^{[11
]}

Harxhi, Arjan ^{[12
]}

Papadopoulos, Antonios ^{[13
]}

Lakatos, Botond ^{[14
]}

Vasylyev, Marta ^{[15
]}

Begovac, Josip ^{[16
]}

Yancheva, Nina ^{[17
]}

Streinu-Cercel, Anca ^{[18
]}

Verhaz, Antonija ^{[19
]}

Gokengin, Deniz ^{[20
]}

Dragovic, Gordana ^{[21
]}

Sojak, Lubomir ^{[22
]}

Skrzat-Klapaczynska, Agata ^{[2
]}

机构：

[1] Tartu Univ Hosp, Dept Infect Dis, EE-50406 Tartu, Estonia

[2] Med Univ Warsaw, Hosp Infect Dis, Dept Adults Infect Dis, PL-02091 Warsaw, Poland

[3] Vilnius Univ, Vilnius Univ Hosp Santaros Klin, Fac Med, Dept Infect Dis & Dermatovenerol, LT-08410 Vilnius, Lithuania

[4] Univ Clin Ctr Sarajevo, Clin Infect Dis, Sarajevo 71000, Bosnia & Herceg

[5] City Clin Hosp Infect Dis, Minsk 220002, BELARUS

[6] AIDS & Clin Immunol Res Ctr, Infect Dis, GE-0160 Tbilisi, Georgia

[7] Charles Univ Prague, Fac Med 1, Dept Infect Dis, Prague 18000, Czech Republic

[8] Fac Hosp Bulovka, Prague 18000, Czech Republic

[9] Inst Epidemiol & Infect Dis, Clin Gromashevsky, UA-01001 Kiev, Ukraine

[10] Victor Babes Clin Hosp Infect & Trop Dis, Bucharest 030303, Romania

[11] Natl AIDS Ctr, Yerevan 0041, Armenia

[12] Med Univ Tirana, Fac Med, Dept Infect Dis, Tirana 1000, Albania

[13] Natl & Kapodistrian Univ Athens, Attikon Univ Hosp, Sch Med, HIV Unit,Dept Internal Med 4, Athens 12462, Greece

[14] Natl Ctr HIV, Natl Inst Hematol & Infect Dis, H-1097 Budapest, Hungary

[15] Lviv Reg Publ Hlth Ctr, HIV Unit, UA-79000 Lvov, Ukraine

[16] Univ Hosp Infect Dis, Zagreb 10000, Croatia

[17] Med Univ Sofia, Dept AIDS Specialized Hosp Act Treatment Infect &, Sofia 1606, Bulgaria

[18] Natl Inst Infect Dis Prof Dr Matei Bals, Bucharest 021105, Romania

[19] Clin Infect Dis Republ Srpska Banja Luka, Banja Luka 78000, Bosnia & Herceg

[20] Ege Univ, Med Fac, Dept Infect Dis & Clin Microbiol, TR-35100 Izmir, Turkiye

[21] Univ Belgrade, Fac Med, Dept Pharmacol Clin Pharmacol & Toxicol, Belgrade 11000, Serbia

[22] Dept Infectol & Geog Med, Bratislava 83305, Slovakia

来源：

VACCINES | 2023年 / 11卷 / 05期

关键词：

HIV; Hepatitis A; Hepatitis B; Hepatitis C; co-infection; vaccination; Central and Eastern Europe; IMMUNODEFICIENCY-VIRUS COINFECTION; INFECTED PATIENTS; FIBROSIS PROGRESSION; VIRAL-HEPATITIS; CARE;

D O I：

10.3390/vaccines11050980

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

(1) Background: Viral hepatitis C (HCV) and viral hepatitis B (HBV) are common co-infections in people living with HIV (PLWH). All PLWH should be vaccinated against HBV and hepatitis A (HAV) and treated for HBV and HCV. We aimed to compare testing, prophylaxis and treatment of viral hepatitis in PLWH in Central and Eastern Europe (CEE) in 2019 and 2022. (2) Methods: Data was collected through two on-line surveys conducted in 2019 and 2022 among 18 countries of the Euroguidelines in CEE (ECEE) Network Group. (3) Results: In all 18 countries the standard of care was to screen all PLWH for HBV and HCV both years; screening of HAV was routine in 2019 in 54.5% and in 2022 47.4% of clinics. Vaccination of PLWH against HAV was available in 2019 in 16.7%, in 2022 in 22.2% countries. Vaccination against HBV was available routinely and free of charge in 50% of clinics both in 2019 and 2022. In HIV/HBV co-infected the choice of NRTI was tenofovir-based in 94.4% of countries in both years. All clinics that responded had access to direct-acting antivirals (DAAs) but 50% still had limitations for treatment. (4) Conclusions: Although testing for HBV and HCV was good, testing for HAV is insufficient. Vaccination against HBV and especially against HAV has room for improvement; furthermore, HCV treatment access needs to overcome restrictions.

引用

页数：9

共 38 条

[1]

[Anonymous], SHORT DUR PAN GEN TH

[2]

[Anonymous], EM OPP CHALL HIV PRE

[3]

[Anonymous], VACC SCHED

[4]

[Anonymous], EACS GUID

[5]

[Anonymous], WHO IMM DAT PORT

[6]

[Anonymous], MAN AC HCV INF HCV G

[7]

[Anonymous], Clinical manifestations and diagnosis of echinococcosis

[8]

[Anonymous], FULL ART VACC COV PL, DOI [10.1080/21645515.2018.1534517, DOI 10.1080/21645515.2018.1534517]

[9] Recently acquired and early chronic hepatitis C in MSM: Recommendations from the European treatment network for HIV, hepatitis and global infectious diseases consensus panel [J].

Boesecke, Christoph .

AIDS, 2020, 34 (12) :1699-1711

[10] Implementation of EACS vaccination recommendations among people living with HIV [J].

Breitschwerdt, Sven ;

Schwarze-Zander, Carolynne ;

Al Tayy, Ahmad ;

Mutevelli, Julia ;

Wasmuth, Jan-Christian ;

Rockstroh, Jurgen K. ;

Boesecke, Christoph .

INFECTION, 2022, 50 (06) :1491-1497

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