Diagnostic value of colour Doppler ultrasound in differentiating malignant and benign nodules in thyroiditis background

被引:0
作者
Alamdaran, Seyed Ali [1 ]
Farshidianfar, Melika [2 ]
Masoumi, Alireza [2 ]
Rashed, Masoud Mahdavi [1 ]
Jaberi, Masoumeh [1 ]
机构
[1] Mashhad Univ Med Sci, Fac Med, Dept Radiol, 85 Honarestan 29,Honarestan Blv,Khorasan E Razavi, Mashhad, Iran
[2] Islamic Azad Univ, Fac Med, Mashhad Branch, Mashhad, Iran
关键词
Colour Doppler ultrasound; thyroid neoplasm; thyroiditis; ultrasound; POWER DOPPLER; SONOGRAPHIC FEATURES; ULTRASONOGRAPHY; RISK; US; CANCER;
D O I
10.1002/jmrs.751
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
IntroductionDifferentiating malignant thyroid nodules from benign ones is challenging. Sonography is a non-invasive modality that can be helpful in this regard and is far better than invasive methods like fine needle aspiration (FNA). This study aimed to assess the diagnostic value of colour Doppler ultrasonography in distinguishing malignant and benign nodules of thyroid gland.MethodsThe study involved patients with thyroiditis and thyroid nodules, who underwent sonography. Ultrasound findings were assessed. All the nodules were classified according to the FNA into malignant, follicular nodules and lymphatic. Then, sonography findings were compared between these three groups.ResultsThere were 216 nodules, including 108 (50%) malignant nodules, 80 (37%) benign and 28 (13%) lymphatic follicles, were evaluated. Micro-calcification was present in 50 (46.3%) malignant cases, 11 (13.7%) benign cases and 2 (2.1%) lymphatic follicles. Decreased or mixed vascularity was reported in 43 (69%) malignant nodules, 4 (5%) benign cases and 7 (25%) lymphatic follicles. Also, 9.7% and 42% of malignant and benign nodules had peripheral circular vascularity, respectively; however, none of the lymphatic follicles had this finding. With 89% specificity, 49% sensitivity and 73.5% accuracy, calcification with or without decreased or mixed vascularity could differentiate benign and malignant nodules.ConclusionDecreased or mixed vascularity with or without calcification shows high sensitivity in differentiating malignant and benign nodules. Our results demonstrated that the addition of colour Doppler to routine sonography is helpful in differentiating malignant nodules from benign ones. image
引用
收藏
页码:233 / 239
页数:7
相关论文
共 24 条
[11]   Risk for malignancy of thyroid nodules as assessed by sonographic criteria - The need for biopsy [J].
Iannuccilli, JD ;
Cronan, JJ ;
Monchik, JM .
JOURNAL OF ULTRASOUND IN MEDICINE, 2004, 23 (11) :1455-1464
[12]  
Majety P., 2000, Endotext
[13]   Can Vascularity at Power Doppler US Help Predict Thyroid Malignancy? [J].
Moon, Hee Jung ;
Kwak, Jin Young ;
Kim, Min Jung ;
Son, Eun Ju ;
Kim, Eun-Kyung .
RADIOLOGY, 2010, 255 (01) :260-269
[14]   Ultrasonographic findings of papillary thyroid carcinoma with Hashimoto's thyroiditis [J].
Ohmori, Nariko ;
Miyakawa, Megumi ;
Ohmori, Kazue ;
Takano, Kazue .
INTERNAL MEDICINE, 2007, 46 (09) :547-550
[15]   Sonographic Features of Nodular Hashimoto Thyroiditis [J].
Oppenheimer, Daniel Corey ;
Giampoli, Ellen ;
Montoya, Simone ;
Patel, Swapnil ;
Dogra, Vikram .
ULTRASOUND QUARTERLY, 2016, 32 (03) :271-276
[16]   Risk of malignancy in nonpalpable thyroid nodules: Predictive value of ultrasound and color-Doppler features [J].
Papini, E ;
Guglielmi, R ;
Bianchini, A ;
Crescenzi, A ;
Taccogna, S ;
Nardi, F ;
Panunzi, C ;
Rinaldi, R ;
Toscano, V ;
Pacella, CM .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2002, 87 (05) :1941-1946
[17]   Ultrasonography: Is it useful in the diagnosis of cancer in thyroid nodules? [J].
Peccin, S ;
de Castro, JAS ;
Furlanetto, TW ;
Furtado, APA ;
Brasil, BA ;
Czepielewski, MA .
JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2002, 25 (01) :39-43
[18]  
Phuttharak W, 2009, ASIAN PAC J CANCER P, V10, P759
[19]  
Salehi M., 2015, GLOBAL J HLTH SCI, V7, P147
[20]   US, colour-Doppler US and fine-needle aspiration biopsy in the diagnosis of thyroid nodules [J].
Stacul F. ;
Bertolotto M. ;
De Gobbis F. ;
Calderan L. ;
Cioffi V. ;
Romano A. ;
Zanconati F. ;
Cova M.A. .
La radiologia medica, 2007, 112 (5) :751-762