Unexplained visual loss in retinal detachment repair: comparing gas, silicone oil and heavy silicone oil by multivariable regression.

被引：3

作者：

Moussa, George ^{[1
,2
,4
]}

Tadros, Maria ^{[1
,2
]}

Ch'ng, Soon Wai ^{[1
,2
]}

Ferrara, Mariantonia ^{[4
]}

Kalogeropoulos, Dimitrios ^{[3
,5
]}

Sharma, Ash ^{[3
]}

Lett, Kim Son ^{[3
]}

Mitra, Arijit ^{[3
]}

Tyagi, Ajai K. ^{[3
]}

Andreatta, Walter ^{[3
,6
,7
]}

机构：

[1] Univ Birmingham, Birmingham & Midland Eye Ctr, Birmingham, England

[2] Univ Birmingham, Acad Unit Ophthalmol, Birmingham, England

[3] Sandwell & West Birmingham Hosp NHS Trust, Birmingham Midlands Eye Ctr, Dudley Rd, Birmingham B18 7QH, England

[4] Manchester Royal Eye Hosp, Oxford Rd, Manchester M13 9WL, England

[5] Univ Ioannina, Fac Med, Sch Hlth Sci, Dept Ophthalmol, Ioannina, Greece

[6] Kantonsspital Winterthur, Brauerstr 15, CH-8400 Winterthur, Switzerland

[7] Univ Zurich, Ramistr 71, CH-8006 Zurich, Switzerland

来源：

INTERNATIONAL JOURNAL OF RETINA AND VITREOUS | 2023年 / 9卷 / 01期

关键词：

Retinal detachment; Gas; Silicone oil; Heavy silicone oil; Densiron; 68; Retina; vitreoretinal; Unexplained visual loss; OPTICAL COHERENCE TOMOGRAPHY; TAMPONADE; OUTCOMES;

D O I：

10.1186/s40942-023-00466-9

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

PurposeTo measure the proportion of unexplained and all causes of visual loss following primary rhegmatogenous-retinal-detachment (RRD) repair, comparing gas tamponade (SF6, C2F6, C3F8), silicone oil (SO, 1000cs and 5000cs) and heavy silicone oil (Densiron).MethodsRetrospective, continuous, comparative study from 01/1/2017-31/5/2021. All primary RRDs were included after successful removal of SO and Densiron. Primary failures were excluded. Visual loss was defined as reduction of >= 0.30 logMAR units. Multivariable binary-logistic and linear regression models to compare tamponade, and all cases of unexplained visual loss and logMAR gain were performed. Covariates included age, ocular co-morbidities, pre-op vision, macula-status, high-myopia, giant-retinal-tear (GRT), perfluorocarbon-use, combined buckle/PPV, PVR-C, retinectomy, tamponade agent and post-operative lens status.ResultsOf 1,012 primary RRDs, we found an incidence of unexplained visual loss in 15/1012 (1.5%, SF6:1/341[0.3%], C2F6:4/338[1.2%], C3F8:2/239[0.8%], Densiron:0/33[0.0%], SO-1000cs:5/43[11.6%] and SO-5000cs:3/18[16.7%]), and visual loss of all causes in 57/1012 (5.6%, SF6:13/341[3.8%], C2F6:14/338[4.1%], C3F8:15/239[6.3%], Densiron:2/33[6.1%], SO-1000cs:9/43[20.9%] and SO-5000cs:4/18[22.2%]). On multivariable binary-logistic regression, we report that macula-on RRD (Odds-Ratio[OR]5.7,95% Confidence-interval[CI]1.2-28.2, p=0.032), GRT (OR35.0,CI 2.0-617.3, p=0.015), combined buckle/PPV (OR37.7,CI 2.0-711.4, p=0.015), SO1000cs (OR86.6,CI 5.6-1,348.0), p=0.001) and 5000cs (OR37.2,CI 1.3-1,101.5, p=0.036) (Reference-tamponade:SF6) were associated with unexplained visual loss. Duration of oil tamponade was not linked to increase in unexplained visual loss (p=0.569).ConclusionsCorrelation between SO in detachment repairs and unexplained visual loss has been established, however incidence with HSO has not been compared to other agents. This study demonstrates that although SO was linked with risk-adjusted increased unexplained visual loss relative to gas tamponade, no such association was found for Densiron, on multivariable analysis.

引用

页数：10

共 32 条

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