Crystal structures of 4-[(4-methylbenzyl)oxy]benzohydrazide and its N'-[(thiophen-2-yl)methylidene]- derivative

被引：4

作者：

Al Banna, Md Hasan ^{[1
]}

Howlader, Md Belayet Hossain ^{[1
]}

Miyatake, Ryuta ^{[2
]}

Sheikh, Md Chanmiya ^{[3
]}

Ansary, Md Rezaul Haque ^{[1
]}

Zangrando, Ennio ^{[4
]}

机构：

[1] Rajshahi Univ, Dept Chem, Rajshahi 6205, Bangladesh

[2] Univ Toyama, Ctr Environm Conservat & Res Safety, 3190 Gofuku, Toyama 9308555, Japan

[3] Okayama Univ Sci, Fac Sci, Dept Appl Sci, Okayama, Japan

[4] Univ Trieste, Dept Chem & Pharmaceut Sci, Trieste, Italy

来源：

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2023年 / 79卷

关键词：

crystal structure; hydrazine; hydrazone; HYDRAZONES;

D O I：

10.1107/S2056989023001354

中图分类号：

O7 [晶体学];

学科分类号：

0702 ; 070205 ; 0703 ; 080501 ;

摘要：

The molecular and crystal structures of a benzoylhydrazine bearing an ether group, 4-[(4-methylbenzyl)oxy]benzohydrazide, C15H16N2O2, (I), and of the corresponding N0-[(thiophen-2-yl)methylidene]- derivative, 4-[(4-methylbenzyl)oxy]-N'-[(thiophen-2-yl)methylidene]benzohydrazide, C20H18N2O2S, (II), are described. The supramolecular structures of both compounds are governed by N-H center dot center dot center dot N and N-H center dot center dot center dot O hydrogen-bonding interactions. The hydrazine compound (I) shows a crystal packing with a more complex hydrogen-bonding scheme because of the NH-NH2 entity, forming a di-periodic supramolecular structure extending parallel to (100). Hydrazone molecules in (II) are hydrogenbonded through N-H center dot center dot center dot O interactions, giving rise to the formation of ribbons parallel to [010]. Molecules of (I) and (II) show a different orientation of the carbohydrazide moiety likely to favor the crystal packing and thus hydrogenbonding interactions.

引用

页码：207 / +

页数：14

共 22 条

[11] The bioactivity of benzenesulfonyl hydrazones: A short review [J].

Popiolek, Lukasz .

BIOMEDICINE & PHARMACOTHERAPY, 2021, 141

[12]

Rigaku, 2018, Rapid auto

[13]

Sandler S. R., 1992, SOURCEBOOK ADV ORGAN

[14] SHELXT - Integrated space-group and crystal-structure determination [J].

Sheldrick, George M. .

ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES, 2015, 71 :3-8

[15]

Sheldrick GM, 2015, ACTA CRYSTALLOGR C, V71, P3, DOI [10.1107/S2053273314026370, 10.1107/S2053229614024218, 10.1107/S0108767307043930]

[16]

Sinha Birandra K, 2014, J Drug Metab Toxicol, V5, DOI 10.4172/2157-7609.1000168

[17] Synthesis and evaluation of analgesic, antiinflammatory and antiplatelet properties of new 2-pyridylarylhydrazone derivatives [J].

Todeschini, AR ;

de Miranda, ALP ;

da Silva, KCM ;

Parrini, SC ;

Barreiro, EJ .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 1998, 33 (03) :189-199

[18] Hydrazones of 1,2-benzisothiazole hydrazides: synthesis, antimicrobial activity and QSAR investigations [J].

Vicini, P ;

Zani, F ;

Cozzini, P ;

Doytchinova, I .

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2002, 37 (07) :553-564

[19] (E)-N '-(2-Chlorobenzylidene)-1-methyl4-nitro-1H-pyrrole-2-carbohydrazide [J].

Wang, Jinglin ;

He, Rong ;

Xin, Zhijuan ;

Shen, Huiling ;

Wang, Cairong .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 :O99-+

[20] Crystal structure of (E)-N '-benzylidene-1-methyl-4-nitro-1H-pyrrole-2-carbohydrazide [J].

Wang, Zhijun ;

Zhou, Chengyong ;

Yan, Lei ;

Wang, Jinglin .

ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2014, 70 :O995-+

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