Factors and Methods for the Detection of Gene Expression Regulation

被引:4
作者
Wang, Mengyuan [1 ]
Li, Qian [1 ]
Liu, Lingbo [1 ]
机构
[1] Huazhong Univ Sci & Technol, Union Hosp, Inst Hematol, Tongji Med Coll, Wuhan 430022, Peoples R China
基金
中国国家自然科学基金;
关键词
gene expression regulation; detection methods; transcription factors; epigenetics; MESSENGER-RNA METHYLATION; I HYPERSENSITIVE SITES; DNA METHYLATION; CHROMATIN-STRUCTURE; CROSS-LINKING; NUCLEAR-RNA; NUCLEOSOME OCCUPANCY; HIGH-THROUGHPUT; GENOME; WIDE;
D O I
10.3390/biom13020304
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Gene-expression regulation involves multiple processes and a range of regulatory factors. In this review, we describe the key factors that regulate gene expression, including transcription factors (TFs), chromatin accessibility, histone modifications, DNA methylation, and RNA modifications. In addition, we also describe methods that can be used to detect these regulatory factors.
引用
收藏
页数:21
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