Clinical practice of UroVysion® urine test in patients with bladder carcinoma in situ treated with intravesical Bacillus Calmette-Guerin

被引：1

作者：

Miyake, Makito ^{[1
,4
]}

Hori, Shunta ^{[1
]}

Fujii, Tomomi ^{[2
]}

Nishimura, Nobutaka ^{[1
]}

Oda, Yuki ^{[1
]}

Miyamoto, Tatsuki ^{[1
]}

Tomizawa, Mitsuru ^{[1
]}

Shimizu, Takuto ^{[1
]}

Ohnishi, Kenta ^{[1
]}

Morizawa, Yosuke ^{[1
]}

Gotoh, Daisuke ^{[1
]}

Nakai, Yasushi ^{[1
]}

Torimoto, Kazumasa ^{[1
]}

Tanaka, Nobumichi ^{[1
,3
]}

Fujimoto, Kiyohide ^{[1
]}

机构：

[1] Nara Med Univ, Dept Urol, Kashihara, Japan

[2] NaraMed Univ, Dept Diagnost Pathol, Kashihara, Japan

[3] Nara Med Univ, Dept Prostate Brachytherapy, Kashihara, Japan

[4] Nara Med Univ, Dept Urol, 840 Shijo Cho, Nara 6348522, Japan

来源：

JAPANESE JOURNAL OF CLINICAL ONCOLOGY | 2023年 / 53卷 / 07期

关键词：

bladder cancer; carcinoma in situ; Bacillus Calmette-Guerin; cytology; FISH; DIAGNOSIS;

D O I：

10.1093/jjco/hyad029

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In January 2019, the use of the UroVysion (R) urine test for surveillance of non-muscle invasive bladder cancer with carcinoma in situ (CIS) was approved in Japan. Clinical evidence of its use remains limited. Herein, we report the real-world clinical practice of the UroVysion test. Of 29 patients underwent at least one UroVysion test at our hospital from 2019 to 2022, only two (6.9%) tested positive without any visible tumor on the cystoscopy after the initial transurethral resection: a 77-year-old man with T1 high-grade tumor and concomitant CIS and a 76-year-old woman with CIS. The remaining 27 patients (93.1%) tested negative post-transurethral resection. This study was the first to report the Japanese real-world practice of the UroVysion test, demonstrating relatively low positive rate as compared to the previous reports from other countries. Further clinical evidence from other Japanese institutes needs to be accumulated to update the true value of this test.

引用

页码：629 / 632

页数：4

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