Dynamics of a diffusion dispersal viral epidemic model with age infection in a spatially heterogeneous environment with general nonlinear function

被引:9
作者
Mahroug, Fatima [1 ,2 ]
Bentout, Soufiane [1 ,3 ]
机构
[1] Univ Tlemcen, Lab Anal Non Lineaire & Math Appl, Tilimsen 13000, Algeria
[2] Abou Bekr Belkaid Tlemcen Univ, Fac Sci, Math Dept, Tilimsen, Algeria
[3] Ain Temouchent Univ, Dept Math & Informat, Ain Temouchent, Algeria
关键词
age structured; Fickian diffusion; heterogeneous environment; infectious viral; Lyapunov functional; nonlinear incidence; ASYMPTOTIC PROFILES; GLOBAL STABILITY; STEADY-STATES; MATHEMATICAL-ANALYSIS; HIV-INFECTION; SIR; DELAY;
D O I
10.1002/mma.9357
中图分类号
O29 [应用数学];
学科分类号
070104 ;
摘要
We propose a generalization of a model with age of infection in a heterogeneous environment. Firstly, we give the well-posedness of the model and prove that the solutions are bounded and positive. The difficult mathematical issue in this research is that the model is partially degenerate, and the solution map is not compact. In addition, we construct a global attractor of a bounded set to establish the existence of total trajectory. Moreover, we define the principal eigenvalue associated with a principal eigenvalue problem to give a relation with the basic reproduction number R-0. By assuming that R-0<1 E-0 is globally asymptotically stable. Furthermore, for R-0>1 and by using the persistence results, we prove the existence of endemic steady-states E* and by constructing an appropriate Lyapunov function, we show that E* is globally asymptotically stable. Lastly, we validate our theoretical analysis by giving some numerical graphics.
引用
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页码:14983 / 15010
页数:28
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