Elderly-onset rheumatoid arthritis vs. polymyalgia rheumatica: Differences in pathogenesis

被引：10
作者：
Wu, Jinzhi [1 ]
Yang, Fan [1 ]
Ma, Xinlei [1 ]
Lin, Jin [1 ]
Chen, Weiqian [1 ]
机构：
[1] Zhejiang Univ, Affiliated Hosp 1, Sch Med, Div Rheumatol, Hangzhou, Zhejiang, Peoples R China
来源：
FRONTIERS IN MEDICINE | 2023年 / 9卷
基金：
中国国家自然科学基金;
关键词：
elderly-onset rheumatoid arthritis; polymyalgia rheumatica; rheumatoid arthritis; pathogenesis; inflammation; GIANT-CELL ARTERITIS; DENDRITIC CELLS; FUNCTIONAL HAPLOTYPES; DISEASE-ACTIVITY; SYNOVIAL TISSUE; EXPRESSION; SUSCEPTIBILITY; SUBSET; PADI4; TH17;
D O I：
10.3389/fmed.2022.1083879
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Rheumatoid arthritis is a chronic autoimmune disease that mainly affects the facet joints. Elderly-onset rheumatoid arthritis appears to exhibit symptoms similar to those of polymyalgia rheumatica, characterized by morning stiffness and pain in the shoulder and hip joints. Both diseases develop in the elderly, and it is sometimes challenging to distinguish them. Here, we identify the differences in pathogenesis between elderly-onset rheumatoid arthritis and polymyalgia rheumatica to assist with a clear differential diagnosis and effective early intervention.
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页数：8
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