Zinc Metal-Organic Frameworks- Graphene Quantum Dots Nanocomposite Mediated Highly Sensitive and Selective Fluorescence "On-Off-On" Probe for Sensing of Quercetin

被引：1
作者：
Nangare, Sopan N. [1 ]
Sangare, Premnath M. [2 ]
Patil, Ashwini G. [3 ]
Patil, Pravin O. [2 ]
机构：
[1] HR Patel Inst Pharmaceut Educ & Res, Dept Pharmaceut, Hirpur 425405, MS, India
[2] HR Patel Inst Pharmaceut Educ & Res Shirpur, Dept Pharmaceut Chem, Shirpur 425405, MS, India
[3] RC Patel Arts Commerce & Sci Coll, Dept Microbiol, Shirpur 425405, MS, India
来源：
ACTA CHIMICA SLOVENICA | 2023年 / 70卷 / 04期
关键词：
Zinc metal-organic frameworks; graphene quantum dots; copper ions; quercetin; high sensitivity; high seensitivity; CARBON DOTS; NANOPARTICLES; ELECTRODE;
D O I：
10.17344/acsi.2022.7870
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The current study presents a fluorescence-based 'On-Off-On' nanoprobe composed of rose petal-derived graphene quantum dots embedded in zinc metal-organic frameworks (RP-GQDs@Zn-MOFs) as a proof of concept for quercetin sensing. The particle size and HR-TEM analysis confirmed the synthesis of a uniformly distributed nanosized probe, while the zeta potential (+33.03 mV) verified its good stability. The fluorescence analysis confirmed that the introduction of copper ions (Cu2+) resulted in fluorescence quenches, while the inclusion of quercetin forms quercetin-Cu2+ complex, leading to recovery of quenched fluorescence in RP-GQDs@Zn-MOFs due to static quenching. The nanoprobe demonstrated a wide concentration range and a low detection limit of 100 ng/mL to 1400 ng/mL (R2 = 0.99) and 37.8 ng/mL, respectively. Selectivity analysis highlighted pronounced specificity for quercetin, attributed to Cu2+ coordination between carbonyl oxygen atom and the 3-OH group of quercetin. Furthermore, designed probe exhibited excellent stability, repeatability (RSD < 5), and potential for real-time analysis.
引用
收藏
页码：661 / 673
页数：13
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共 36 条
  • [11] Synthesis and characterization of ZIF-8 nanoparticles for controlled release of 6-mercaptopurine drug
    Kaur, Harpreet
    Mohanta, Girish C.
    Gupta, Vandana
    Kukkar, Deepak
    Tyagi, Sachin
    [J]. JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY, 2017, 41 : 106 - 112
  • [12] A Sensitive and Selective Electrochemical Sensor Based on Graphene Quantum Dot/Gold Nanoparticle Nanocomposite Modified Electrode for the Determination of Quercetin in Biological Samples
    Li, Jianjun
    Qu, Jiajia
    Yang, Ran
    Qu, Lingbo
    Harrington, Peter de B.
    [J]. ELECTROANALYSIS, 2016, 28 (06) : 1322 - 1330
  • [13] Review of Carbon and Graphene Quantum Dots for Sensing
    Li, Meixiu
    Chen, Tao
    Gooding, J. Justin
    Liu, Jingquan
    [J]. ACS SENSORS, 2019, 4 (07) : 1732 - 1748
  • [14] Synthesis of gold-palladium nanowaxberries/dodecylamine-functionalized graphene quantum dots-graphene micro-aerogel for voltammetric determination of peanut allergen Ara h 1
    Li, Ruiyi
    Liu, Ling
    Zhu, Haiyan
    Li, Zaijun
    [J]. ANALYTICA CHIMICA ACTA, 2018, 1008 : 38 - 47
  • [15] Surface and Bulk Integrations of Single-Layered Au or Ag Nanoparticles onto Designated Crystal Planes {110} or {100} of ZIF-8
    Li, Zheng
    Zeng, Hua Chun
    [J]. CHEMISTRY OF MATERIALS, 2013, 25 (09) : 1761 - 1768
  • [16] Imparting functionality to a metal-organic framework material by controlled nanoparticle encapsulation
    Lu, Guang
    Li, Shaozhou
    Guo, Zhen
    Farha, Omar K.
    Hauser, Brad G.
    Qi, Xiaoying
    Wang, Yi
    Wang, Xin
    Han, Sanyang
    Liu, Xiaogang
    DuChene, Joseph S.
    Zhang, Hua
    Zhang, Qichun
    Chen, Xiaodong
    Ma, Jan
    Loo, Say Chye Joachim
    Wei, Wei D.
    Yang, Yanhui
    Hupp, Joseph T.
    Huo, Fengwei
    [J]. NATURE CHEMISTRY, 2012, 4 (04) : 310 - 316
  • [17] A novel hybrid fluorescence probe sensor based on metal-organic framework@carbon quantum dots for the highly selective detection of 6-mercaptopurine
    Mousavi, Aida
    Zare-Dorabei, Rouholah
    Mosavi, Seyed Hossein
    [J]. ANALYTICAL METHODS, 2020, 12 (44) : 5397 - 5406
  • [18] Design of graphene quantum dots decorated MnO2 nanosheet based fluorescence turn ?On-Off-On? nanoprobe for highly sensitive detection of lactoferrin
    Nangare, Sopan
    Patil, Sagar
    Patil, Sairendhri
    Khan, Zamir
    Patil, Ashwini
    Patil, Pravin
    [J]. INORGANIC CHEMISTRY COMMUNICATIONS, 2022, 143
  • [19] Nanostructured metal-organic framework-based luminescent sensor for chemical sensing: current challenges and future prospects
    Nangare, Sopan N.
    Patil, Ashwini G.
    Chandankar, Sachin M.
    Patil, Pravin O.
    [J]. JOURNAL OF NANOSTRUCTURE IN CHEMISTRY, 2023, 13 (02) : 197 - 242
  • [20] Surface architectured metal organic frameworks-based biosensor for ultrasensitive detection of uric acid: Recent advancement and future perspectives
    Nangare, Sopan N.
    Sangale, Premnath M.
    Patil, Ashwini G.
    Boddu, Sai Hs
    Deshmukh, Prashant K.
    Jadhav, Namdeo R.
    Tade, Rahul S.
    Patil, Dilip R.
    Pandey, Abhijeet
    Mutalik, Srinivas
    Patel, Jayvadan K.
    Patil, Arun M.
    Bari, Sanjaykumar B.
    Patil, Pravin O.
    [J]. MICROCHEMICAL JOURNAL, 2021, 169
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