Zinc Metal-Organic Frameworks- Graphene Quantum Dots Nanocomposite Mediated Highly Sensitive and Selective Fluorescence "On-Off-On" Probe for Sensing of Quercetin

被引：1
作者：
Nangare, Sopan N. [1 ]
Sangare, Premnath M. [2 ]
Patil, Ashwini G. [3 ]
Patil, Pravin O. [2 ]
机构：
[1] HR Patel Inst Pharmaceut Educ & Res, Dept Pharmaceut, Hirpur 425405, MS, India
[2] HR Patel Inst Pharmaceut Educ & Res Shirpur, Dept Pharmaceut Chem, Shirpur 425405, MS, India
[3] RC Patel Arts Commerce & Sci Coll, Dept Microbiol, Shirpur 425405, MS, India
来源：
ACTA CHIMICA SLOVENICA | 2023年 / 70卷 / 04期
关键词：
Zinc metal-organic frameworks; graphene quantum dots; copper ions; quercetin; high sensitivity; high seensitivity; CARBON DOTS; NANOPARTICLES; ELECTRODE;
D O I：
10.17344/acsi.2022.7870
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The current study presents a fluorescence-based 'On-Off-On' nanoprobe composed of rose petal-derived graphene quantum dots embedded in zinc metal-organic frameworks (RP-GQDs@Zn-MOFs) as a proof of concept for quercetin sensing. The particle size and HR-TEM analysis confirmed the synthesis of a uniformly distributed nanosized probe, while the zeta potential (+33.03 mV) verified its good stability. The fluorescence analysis confirmed that the introduction of copper ions (Cu2+) resulted in fluorescence quenches, while the inclusion of quercetin forms quercetin-Cu2+ complex, leading to recovery of quenched fluorescence in RP-GQDs@Zn-MOFs due to static quenching. The nanoprobe demonstrated a wide concentration range and a low detection limit of 100 ng/mL to 1400 ng/mL (R2 = 0.99) and 37.8 ng/mL, respectively. Selectivity analysis highlighted pronounced specificity for quercetin, attributed to Cu2+ coordination between carbonyl oxygen atom and the 3-OH group of quercetin. Furthermore, designed probe exhibited excellent stability, repeatability (RSD < 5), and potential for real-time analysis.
引用
收藏
页码：661 / 673
页数：13
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