Biodegradable elastomers for biomedical applications

被引：36

作者：

Chen, Shuo ^{[1
,2
]}

Wang, Yihan ^{[2
]}

Yang, Lei ^{[2
]}

Chu, Chengzhen ^{[2
]}

Cao, Shichun ^{[2
]}

Wang, Zhao ^{[3
]}

Xue, Jiajia ^{[4
]}

You, Zhengwei ^{[1
,2
]}

机构：

[1] Donghua Univ, Coll Biol Sci & Med Engn, Shanghai Engn Res Ctr Nanobiomat & Regenerat Med, State Key Lab Modificat Chem Fibers & Polymer Mat, Shanghai 201620, Peoples R China

[2] Donghua Univ, Inst Funct Mat, Coll Mat Sci & Engn, Res Base Text Mat Flexible Elect & Biomed Applicat, Shanghai 201620, Peoples R China

[3] South China Univ Technol, Inst Emergent Elastomers, Sch Mat Sci & Engn, Guangzhou 510006, Peoples R China

[4] Beijing Univ Chem Technol, State Key Lab Organ Inorgan Composites, Beijing Lab Biomed Mat, Beijing 100029, Peoples R China

来源：

PROGRESS IN POLYMER SCIENCE | 2023年 / 147卷

基金：

中国国家自然科学基金;

关键词：

Elastomer; Biodegradable; Tissue engineering; Electronics; Adhesive; Biomedicine; SEBACATE) PRE-POLYMER; SHAPE-MEMORY POLYMER; IN-VIVO EVALUATION; POLY(GLYCEROL SEBACATE); MECHANICAL-PROPERTIES; ENZYMATIC DEGRADATION; CITRIC-ACID; INTRINSICALLY PHOTOLUMINESCENT; POLYURETHANE ELASTOMERS; POLY(SEBACOYL DIGLYCERIDE);

D O I：

10.1016/j.progpolymsci.2023.101763

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Synthetic biodegradable elastomers, such as polyesters and polyurethanes have revolutionized biomedical therapeutic strategies and devices. Driven by innovations in chemical synthesis and processing technologies, a series of biodegradable elastomers and corresponding devices with controllable properties and various functionalities have been developed. In this review, we have summarized the recent progress in synthesis, process technologies, and biomedical applications of biodegradable elastomers. Particular emphasis is on the molecular design for biodegradability, elasticity, and the newly developed functionalities including self-healing, antibacterial, fluorescence, and shape-memory of biodegradable polyesters and polyurethane as well as their corresponding processing strategies. Subsequently, the recent progress of biodegradable elastomers in different biomedical applications is reviewed. A comprehensive conclusion and outlook pointing out emerging research directions, future challenges and potential solutions complete this work. (c) 2023 Published by Elsevier Ltd.

引用

页数：45

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