Global burden of peripheral artery disease and its risk factors, 1990-2019: a systematic analysis for the Global Burden of Disease Study 2019

被引：75

作者：

Kim, Min Seo ^{[1
]}

Hwang, Jimin ^{[2
]}

Yon, Dong Keon ^{[3
]}

Lee, Seung Won ^{[4
]}

Jung, Se Yong ^{[5
]}

Park, Seoyeon ^{[6
]}

Johnson, Catherine Owens ^{[7
]}

Stark, Benjamin A. ^{[7
]}

Razo, Christian ^{[7
]}

Abbasian, Mohammadreza ^{[10
,15
]}

Abbastabar, Hedayat ^{[19
]}

Abhari, Amir Parsa ^{[29
]}

Aboyans, Victor ^{[31
,32
]}

Adane, Denberu Eshetie Adane ^{[33
]}

Adebayo, Oladimeji M. ^{[34
]}

Alahdab, Fares

Almustanyir, Sami ^{[38
,39
]}

Aly, Hany ^{[40
]}

Ameyaw, Edward Kwabena ^{[42
]}

Anderson, Jason A. ^{[7
]}

Andrei, Catalina Liliana ^{[43
]}

Aryan, Zahra ^{[11
,20
]}

Aujayeb, Avinash ^{[45
]}

Bagherieh, Sara ^{[29
]}

Baltatu, Ovidiu Constantin ^{[46
,47
]}

Banach, Maciej ^{[48
,49
]}

Bayileyegn, Nebiyou Simegnew ^{[50
]}

Bearne, Lindsay M. ^{[51
,52
]}

Behnoush, Amir Hossein ^{[20
,21
]}

Bensenor, Isabela M. ^{[53
]}

Bhaskar, Sonu ^{[54
,55
,56
]}

Bhat, Ajay Nagesh ^{[57
]}

Bhat, Vivek ^{[58
]}

Bikbov, Boris ^{[59
]}

Bintoro, Bagas Suryo ^{[60
,61
]}

Burkart, Katrin ^{[7
,8
]}

Camera, Luis Alberto ^{[62
,63
]}

Catapano, Alberico L. ^{[64
,65
]}

Chandrasekar, Eeshwar K. ^{[66
]}

Charan, Jaykaran ^{[68
]}

Chattu, Vijay Kumar ^{[69
,70
]}

Chi, Gerald ^{[12
]}

Chukwu, Isaac Sunday ^{[71
]}

Chung, Sheng-Chia ^{[72
,73
]}

Cirillo, Massimo ^{[74
]}

Coberly, Kaleb ^{[7
]}

Costa, Vera Marisa ^{[75
]}

Dadras, Omid ^{[76
]}

Dai, Xiaochen ^{[7
,8
]}

Do, Thanh Chi ^{[79
]}

机构：

[1] Broad Inst MIT & Harvard, Cardiovasc Dis Initiat, Cambridge, MA USA

[2] Johns Hopkins Univ, Dept Epidemiol, Baltimore, MD USA

[3] Kyung Hee Univ, Dept Pediat, Seoul, South Korea

[4] Sungkyunkwan Univ, Dept Precis Med, Suwon, South Korea

[5] Yonsei Univ, Dept Pediat, Coll Med, Seoul 03722, South Korea

[6] Yonsei Univ, Coll Med, Seoul, South Korea

[7] Univ Washington, Inst Hlth Metr & Evaluat, Washington, WA USA

[8] Univ Washington, Dept Hlth Metr Sci, Sch Med, Washington, WA USA

[9] Univ Washington, Div Cardiol, Washington, WA USA

[10] Brigham & Womens Hosp, Dept Orthoped Surg, Boston, MA USA

[11] Brigham & Womens Hosp, Boston, MA USA

[12] Harvard Univ, Div Cardiovasc Med, Boston, MA USA

[13] Harvard Univ, Dept Hlth Policy & Oral Epidemiol, Boston, MA USA

[14] Harvard Univ, Beth Israel Deaconess Med Ctr, Boston, MA USA

[15] Shahid Beheshti Univ Med Sci, Dept Orthopaed Surg, Tehran, Iran

[16] Shahid Beheshti Univ Med Sci, Dept Pharmacol, Tehran, Iran

[17] Shahid Beheshti Univ Med Sci, Urol & Nephrol Res Ctr, Tehran, Iran

[18] Shahid Beheshti Univ Med Sci, Sch Med, Tehran, Iran

[19] Univ Tehran Med Sci, Adv Diagnost & Intervent Radiol Res Ctr, Tehran, Iran

[20] Univ Tehran Med Sci, Noncommunicable Dis Res Ctr, Tehran, Iran

[21] Univ Tehran Med Sci, Sch Med, Tehran, Iran

[22] Univ Tehran Med Sci, Inst Environm Res, Tehran, Iran

[23] Univ Tehran Med Sci, Cardiac Primary Prevent Res Ctr, Tehran, Iran

[24] Univ Tehran Med Sci, Tehran Heart Ctr, Tehran, Iran

[25] Univ Tehran Med Sci, Students Sci Res Ctr, Tehran, Iran

[26] Univ Tehran Med Sci, Endocrinol & Metab Res Inst, Tehran, Iran

[27] Univ Tehran Med Sci, Dept Cardiol, Tehran, Iran

[28] Univ Tehran Med Sci, Digest Dis Res Inst, Tehran, Iran

[29] Isfahan Univ Med Sci, Sch Med, Esfahan, Iran

[30] Isfahan Univ Med Sci, Cardiac Rehabil Res Ctr, Esfahan, Iran

[31] Dupuytren Univ Hosp, Dept Cardiol, Limoges, France

[32] Univ Limoges, Limoges, France

[33] Debre Tabor Univ, Dept Anesthesia & Crit Care, Debre Tabor, Ethiopia

[34] Univ Coll Hosp, Coll Med, Ibadan, Nigeria

[35] Univ Coll Hosp, Dept Community Med, Ibadan, Nigeria

[36] Univ Coll Hosp, Dept Med, Ibadan, Nigeria

[37] Mayo Clin Fdn Med Educ & Res, Evidence Based Practice Ctr, Dept Cardiovasc Med, Rochester, MN USA

[38] Alfaisal Univ, Coll Med, Riyadh, Saudi Arabia

[39] Minist Hlth, Riyadh, Saudi Arabia

[40] Cleveland Clin, Dept Pediat, Cleveland, OH USA

[41] Cleveland Clin, Lerner Res Inst, Cleveland, OH USA

[42] Lingnan Univ, Sch Grad Studies, Hong Kong, Peoples R China

[43] Carol Davila Univ Med & Pharm, Dept Cardiol, Bucharest, Romania

[44] Carol Davila Univ Med & Pharm, Dept Internal Med, Bucharest, Romania

[45] Northumbria HealthCare Natl Hlth Serv NHS Fdn Tru, NHS Scotland, Newcastle Upon Tyne, Tyne & Wear, England

[46] Khalifa Univ, Dept Pharmacol & Therapeut, Abu Dhabi, U Arab Emirates

[47] Anhembi Morumbi Univ, Ctr Innovat Technol & Educ, Sao Jose Dos Campos, Brazil

[48] Med Univ Lodz, Dept Hypertens, Lodz, Poland

[49] Polish Mothers Mem Hosp Res Inst, Lodz, Poland

[50] Jimma Univ, Dept Surg, Jimma, Ethiopia

来源：

LANCET GLOBAL HEALTH | 2023年 / 11卷 / 10期

基金：

英国医学研究理事会;

关键词：

EPIDEMIOLOGIC TRANSITION; 195; COUNTRIES; SEX; PREVALENCE; TERRITORIES; DISABILITY; MORTALITY;

D O I：

10.1016/S2214-109X(23)00355-8

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Background Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures.Methods Data on peripheral artery disease were modelled using the Global Burden of Disease, Injuries, and Risk Factors Study (GBD) 2019 database. Prevalence, disability-adjusted life years (DALYs), and mortality estimates of peripheral artery disease were extracted from GBD 2019. Total DALYs and age-standardised DALY rate of peripheral artery disease attributed to modifiable risk factors were also assessed.Findings In 2019, the number of people aged 40 years and older with peripheral artery disease was 113 million (95% uncertainty interval [UI] 99 center dot 2-128 center dot 4), with a global prevalence of 1 center dot 52% (95% UI 1 center dot 33-1 center dot 72), of which 42 center dot 6% was in countries with low to middle Socio-demographic Index (SDI). The global prevalence of peripheral artery disease was higher in older people, (14 center dot 91% [12 center dot 41-17 center dot 87] in those aged 80-84 years), and was generally higher in females than in males. Globally, the total number of DALYs attributable to modifiable risk factors in 2019 accounted for 69 center dot 4% (64 center dot 2-74 center dot 3) of total peripheral artery disease DALYs. The prevalence of peripheral artery disease was highest in countries with high SDI and lowest in countries with low SDI, whereas DALY and mortality rates showed U-shaped curves, with the highest burden in the high and low SDI quintiles.Interpretation The total number of people with peripheral artery disease has increased globally from 1990 to 2019. Despite the lower prevalence of peripheral artery disease in males and low-income countries, these groups showed similar DALY rates to females and higher-income countries, highlighting disproportionate burden in these groups. Modifiable risk factors were responsible for around 70% of the global peripheral artery disease burden. Public measures could mitigate the burden of peripheral artery disease by modifying risk factors.Funding Bill & Melinda Gates Foundation.Copyright (c) 2023 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license.

引用

页码：E1553 / E1565

页数：13

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