The Role of Micronutrients in Neurological Disorders

被引:13
作者
Brodska, Helena Lahoda [1 ,2 ]
Klempir, Jiri [3 ,4 ,5 ]
Zavora, Jan [1 ,2 ,6 ,8 ]
Kohout, Pavel [7 ]
机构
[1] Charles Univ Prague, Fac Med 1, Inst Med Biochem & Lab Diagnost, U Nemocnice 499-2, Prague 12808, Czech Republic
[2] Gen Univ Hosp Prague, U Nemocnice 499-2, Prague 12808, Czech Republic
[3] Charles Univ Prague, Fac Med 1, Dept Neurol, Katerinska 30, Prague 12000, Czech Republic
[4] Charles Univ Prague, Fac Med 1, Ctr Clin Neurosci, Katerinska 30, Prague 12000, Czech Republic
[5] Gen Univ Hosp Prague, Katerinska 30, Prague 12000, Czech Republic
[6] Palacky Univ, Fac Med & Dent, Dept Microbiol, Hnevotinska 3, Olomouc, Czech Republic
[7] Charles Univ Prague, Fac Med 3, Clin Internal Med, Videnska 800, Prague 14059, Czech Republic
[8] Thomayer Univ Hosp, Videnska 800, Prague 14059, Czech Republic
关键词
micronutrients; neurodegenerative disorders; autoimmune disorders; stroke; Parkinson's disease; Huntington's disease; neuropathy; multiple sclerosis; epilepsy; VITAMIN-C; PARKINSONS-DISEASE; MULTIPLE-SCLEROSIS; DIETARY-INTAKE; RISK; SUPPLEMENTATION; MECHANISMS; STROKE; INJURY; NEUROPATHOLOGY;
D O I
10.3390/nu15194129
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Trace elements and vitamins, collectively known as micronutrients, are essential for basic metabolic reactions in the human body. Their deficiency or, on the contrary, an increased amount can lead to serious disorders. Research in recent years has shown that long-term abnormal levels of micronutrients may be involved in the etiopathogenesis of some neurological diseases. Acute and chronic alterations in micronutrient levels may cause other serious complications in neurological diseases. Our aim was to summarize the knowledge about micronutrients in relation to selected neurological diseases and comment on their importance and the possibilities of therapeutic intervention in clinical practice.
引用
收藏
页数:18
相关论文
共 105 条
[21]   Nutritional status in chronic spinal cord injury: a systematic review and meta-analysis [J].
Farkas, Gary J. ;
Pitot, Marika A. ;
Berg, Arthur S. ;
Gater, David R. .
SPINAL CORD, 2019, 57 (01) :3-17
[22]   Role of micronutrients in Alzheimer's disease: Review of available evidence [J].
Fei, Hong-Xin ;
Qian, Chao-Fan ;
Wu, Xiang-Mei ;
Wei, Yu-Hua ;
Huang, Jin-Yu ;
Wei, Li-Hua .
WORLD JOURNAL OF CLINICAL CASES, 2022, 10 (22) :7631-7641
[23]   Modulation of cholinergic systems by manganese [J].
Finkelstein, Yoram ;
Milatovic, Dejan ;
Aschner, Michael .
NEUROTOXICOLOGY, 2007, 28 (05) :1003-1014
[24]  
Gomes ABAGR, 2022, ARQ NEURO-PSIQUIAT, V80, P137, DOI [10.1590/0004-282X-ANP-2022-S109, 10.1590/0004-282x-anp-2022-s109]
[25]   Niacin in the Central Nervous System: An Update of Biological Aspects and Clinical Applications [J].
Gasperi, Valeria ;
Sibilano, Matteo ;
Savini, Isabella ;
Catani, Maria Valeria .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2019, 20 (04)
[26]   Nutrition and neurodegeneration: epidemiological evidence and challenges for future research [J].
Gillette-Guyonnet, Sophie ;
Secher, Marion ;
Vellas, Bruno .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2013, 75 (03) :738-755
[27]   Modeling Parkinson's Disease With the Alpha-Synuclein Protein [J].
Gomez-Benito, Monica ;
Granado, Noelia ;
Garcia-Sanz, Patricia ;
Michel, Anne ;
Dumoulin, Mireille ;
Moratalla, Rosario .
FRONTIERS IN PHARMACOLOGY, 2020, 11
[28]   Restless Legs Syndrome: Contemporary Diagnosis and Treatment [J].
Gossard, Thomas R. ;
Trotti, Lynn Marie ;
Videnovic, Aleksandar ;
St Louis, Erik K. .
NEUROTHERAPEUTICS, 2021, 18 (01) :140-155
[29]   Nutraceutical Approaches of Autophagy and Neuroinflammation in Alzheimer's Disease: A Systematic Review [J].
Gruendler, Reinhard ;
Hippe, Berit ;
Jengic, Vesna Sendula ;
Peterlin, Borut ;
Haslberger, Alexander G. .
MOLECULES, 2020, 25 (24)
[30]   Role of diet in stroke incidence: an umbrella review of meta-analyses of prospective observational studies [J].
Guo, Na ;
Zhu, Ying ;
Tian, Dandan ;
Zhao, Yating ;
Zhang, Chenguang ;
Mu, Changqing ;
Han, Chen ;
Zhu, Ruixia ;
Liu, Xu .
BMC MEDICINE, 2022, 20 (01)