Acute generalized exanthematous pustulosis (AGEP) is a rare severe cutaneous adverse reaction triggered in most cases by drugs. It is characterized by abrupt onset and rapid evolution of fields of sterile pustules on an erythematous background. The role of genetic predisposition in this reactive disorder is being explored. We report the simultaneous occurrence of AGEP in two siblings after being exposed to the same drug.
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Temple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Sussman, Morgan
Napodano, Anthony
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Univ Florida Coll Med, Dept Dermatol, Gainesville, FL 32610 USATemple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Napodano, Anthony
Huang, Simo
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Temple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Huang, Simo
Are, Abhirup
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Univ Florida, Coll Med, Gainesville, FL 32606 USATemple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Are, Abhirup
Hsu, Sylvia
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Temple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Hsu, Sylvia
Motaparthi, Kiran
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Univ Florida Coll Med, Dept Dermatol, Gainesville, FL 32610 USATemple Univ, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
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Temple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Ross, Casey L.
Sheychenko, Alina
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Temple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Sheychenko, Alina
Mollanazar, Nicholas K.
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Temple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Mollanazar, Nicholas K.
Hsu, Sylvia
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Temple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USATemple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA
Hsu, Sylvia
Motaparthi, Kiran
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Univ Florida, Dept Dermatol, Coll Med, 4037 NW 86 Terrace,4th Floor,Room 4119 Springhill, Gainesville, FL 32606 USATemple Univ Hosp & Med Sch, Lewis Katz Sch Med, Dept Dermatol, Philadelphia, PA 19140 USA