Multiple Myeloma in a Young Adult with Renal Involvement

被引:0
作者
Hajji, Meriam [1 ,2 ,3 ]
Barbouch, Samia. [1 ,2 ,3 ]
Goucha, Rim. [2 ,3 ]
Abderrahim, Ezzeddine. [1 ,2 ,3 ]
机构
[1] Charles Nicolle Hosp, Dept Med A, Tunis, Tunisia
[2] Lab Renal Pathol LR00SP01, Tunis, Tunisia
[3] Tunis El Manar Univ, Fac Med Tunis, Tunis, Tunisia
关键词
cast nephropathy; early-onset multiple myeloma; prognosis; renal biopsy; survival; treatment response; STAGING SYSTEM; FEATURES; AGE; DISEASE; POPULATION; SURVIVAL; RATES;
D O I
10.1002/ccr3.6986
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Multiple myeloma (MM) results from malignant plasma cell disorder. It represents approximately 10% of hematological malignancies and it is typically diagnosed in the elderly with a median age of 70 years and has a steep increase in incidence with advancing age. N Engl J Med. 2004, 1860; Clin Interv Aging. 2020, 619. The incidence of MM has been increasing over time, mostly due to population aging. Mayo Clin Proc. 2010, 225 However, certain MMs are diagnosed at young age even under 40 years old (2%). Leuk Lymphoma. 1998, 493; Blood. 2010, 5501. We report a case of a MM in a thirty-four-year-old woman whose circumstance of discovery was acute kidney failure.
引用
收藏
页数:5
相关论文
共 29 条
[1]  
Bellahammou K, 2018, INT J SURG MED, V4, P205, DOI [10.5455/ijsm.multiplemyeloma, DOI 10.5455/IJSM.MULTIPLEMYELOMA]
[2]   Presenting features and prognosis in 72 patients with multiple myeloma who were younger than 40 years [J].
Blade, J ;
Kyle, RA ;
Greipp, PR .
BRITISH JOURNAL OF HAEMATOLOGY, 1996, 93 (02) :345-351
[3]   Renal, hematologic and infectious complications in multiple myeloma [J].
Bladé, J ;
Rosiñol, L .
BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2005, 18 (04) :635-652
[4]   Multiple myeloma in young patients:: Clinical presentation and treatment approach [J].
Bladé, J ;
Kyle, RA .
LEUKEMIA & LYMPHOMA, 1998, 30 (5-6) :493-501
[5]   Epidemiological landscape of young patients with multiple myeloma diagnosed before 40 years of age: the French experience [J].
Caulier, Alexis ;
Roussel, Murielle ;
Morel, Pierre ;
Lombion, Naelle ;
Branco, Benoit ;
Galtier, Jean ;
Hulin, Cyrille ;
Perrot, Aurore ;
Richez, Valentine ;
Michaud, Anne-Victoire ;
Touzeau, Cyrille ;
Doyen, Chantal ;
Mariette, Clara ;
Caillot, Denis ;
Harel, Stephanie ;
Lenain, Pascal ;
Ivanoff, Sarah ;
Fontan, Jean ;
Stoppa, Anne-Marie ;
Manier, Salomon ;
Garderet, Laurent ;
Leleu, Xavier ;
Marolleau, Jean-Pierre ;
Arnulf, Bertrand ;
Avet-Loiseau, Herve ;
Royer, Bruno .
BLOOD, 2021, 138 (25) :2686-2695
[6]   Age 40 Years and Under Does Not Confer Superior Prognosis in Patients with Multiple Myeloma Undergoing Upfront Autologous Stem Cell Transmplant [J].
Cheema, Parneet K. ;
Zadeh, Sahar ;
Kukreti, Vishal ;
Reece, Donna ;
Chen, Christine ;
Trudel, Suzanne ;
Mikhael, Joseph .
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2009, 15 (06) :686-693
[7]   Multiple myeloma in younger patients: the role of age as prognostic factor [J].
Corso, A ;
Klersy, C ;
Lazzarino, M ;
Bernasconi, C .
ANNALS OF HEMATOLOGY, 1998, 76 (02) :67-72
[8]  
DURIE BGM, 1975, CANCER, V36, P842, DOI 10.1002/1097-0142(197509)36:3<842::AID-CNCR2820360303>3.0.CO
[9]  
2-U
[10]   Foreword [J].
Eckardt, Kai-Uwe ;
Kasiske, Bertram L. .
KIDNEY INTERNATIONAL SUPPLEMENTS, 2012, 2 (01) :7-7