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Impact of Precision Medicine in Oncology Immuno-oncology
被引:0
作者:
Buchbinder, Elizabeth I.
[1
,2
,3
,5
]
Hodi, F. Stephen
[1
,2
,3
,4
]
机构:
[1] Dana Farber Canc Inst, Dana Farber Canc Inst, Dept Med Oncol, Boston, MA USA
[2] Brigham & Womens Hosp, Dana Farber Canc Inst, Dept Med, Boston, MA USA
[3] Harvard Med Sch, Dana Farber Canc Inst, Boston, MA USA
[4] Dana Farber Canc Inst, Ctr Immuno Oncol, Boston, MA USA
[5] 450 Brookline Ave, Boston, MA 02215 USA
关键词:
CAR-T cell;
immune checkpoint inhibition;
immunotherapy;
cellular therapy;
cytokine;
TIL therapy;
INTERLEUKIN-2 HD IL-2;
RENAL-CELL CARCINOMA;
METASTATIC MELANOMA;
T-CELLS;
PD-1;
CTLA-4;
THERAPY;
IMMUNOTHERAPY;
IPILIMUMAB;
BLOCKADE;
D O I:
10.1097/PPO.0000000000000641
中图分类号:
R73 [肿瘤学];
学科分类号:
100214 ;
摘要:
Cancer treatment has dramatically changed over the last decade with the development of immunotherapy. Therapies including immune cytokines, immune checkpoint inhibition, intratumoral therapies, and cellular therapies are already widely used in the oncology clinic. Active development continues in these areas and in the development of vaccines, bispecific therapies, and more refined cellular therapies. In this review, we will examine the role that immune therapy has in cancer treatment and explore areas of future development.
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页码:15 / 19
页数:5
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