Continuous-time Markov-chain models for reaction systems: fast and slow processes

被引:1
|
作者
MacDonald, Iain L. L. [1 ]
Pienaar, Etienne A. D. [2 ]
机构
[1] Univ Cape Town, Ctr Actuarial Res, ZA-7701 Rondebosch, South Africa
[2] Univ Cape Town, Dept Stat Sci, ZA-7701 Rondebosch, South Africa
关键词
Reaction networks; Markov chain; Continuous time; Fast and slow processes;
D O I
10.1007/s11144-023-02440-w
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
It is sometimes of interest to identify the fast and slow processes in a reaction system. We present here an approach to this problem which is based on a simple stochastic model, a continuous-time Markov chain on a small number of states. We show how it is possible to use such a stochastic model to find and plot the time-courses of concentrations, and to find simple short-time and long-time approximations to these time-courses; that is, to separate the fast and the slow processes. The most significant computation involved is the exponentiation of many small matrices, which is easily accomplished in the computing environment R.
引用
收藏
页码:1757 / 1773
页数:17
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