Coronary Artery Disease and Prognosis of Heart Failure with Reduced Ejection Fraction

被引：6

作者：

Vicent, Lourdes ^{[1
]}

Alvarez-Garcia, Jesus ^{[2
]}

Vazquez-Garcia, Rafael ^{[3
]}

Gonzalez-Juanatey, Jose R. ^{[4
]}

Rivera, Miguel ^{[5
]}

Segovia, Javier ^{[6
]}

Pascual-Figal, Domingo ^{[7
,8
]}

Bover, Ramon ^{[9
]}

Worner, Fernando ^{[10
]}

Fernandez-Aviles, Francisco ^{[1
,11
]}

Ariza-Sole, Albert ^{[12
]}

Martinez-Selles, Manuel ^{[1
,10
,13
,14
]}

机构：

[1] Hosp Univ 12 Octubre, Cardiol Dept, Madrid 28041, Spain

[2] Hosp Santa Creu & Sant Pau, CIBERCV, Cardiol Dept, Barcelona 08025, Spain

[3] Puerta Mar Univ Hosp, Cardiol Dept, Cadiz 11009, Spain

[4] Hosp Clin Univ Santiago, Cardiol Dept, CIBERCV, Santiago De Compostela 15076, Spain

[5] Univ Hosp La Fe, Cardiol Dept, Valencia 46026, Spain

[6] Hosp Univ Puerta Hierro Majadahonda, Cardiol Dept, CIBERCV, Madrid 28222, Spain

[7] Univ Murcia, Hosp Virgen Arrixaca, Cardiol Dept, Dept Med, Murcia 30120, Spain

[8] Ctr Nacl Invest Cardiovasc Carlos III CNIC, Madrid 28029, Spain

[9] Hosp Clin San Carlos, Cardiol Dept, Madrid 28040, Spain

[10] Hosp Arnau Vilanova, Serv Cardiol, Lleida 25198, Spain

[11] Hosp Gen Univ Gregorio Maranon, Cardiol Dept, Inst Invest, CIBERCV, Madrid 28007, Spain

[12] Bellvitge Univ Hosp Gen, Cardiol Dept, Lhospitalet De Llobregat 08907, Barcelona, Spain

[13] Univ Complutense, Fac Med, Madrid 28040, Spain

[14] Univ Europea, Fac Med, Madrid 28670, Spain

来源：

JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 08期

关键词：

heart failure; dilated cardiomyopathy; mortality; readmissions; ischemic heart disease; coronary artery disease; INTERNATIONAL SOCIETY; MYOCARDIAL-INFARCTION; SYSTOLIC DYSFUNCTION; MORTALITY; CARDIOMYOPATHY; SURVIVAL; TRANSPLANTATION; VALIDATION; MORBIDITY; CAPTOPRIL;

D O I：

10.3390/jcm12083028

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Our aim was to determine the prognostic impact of coronary artery disease (CAD) on heart failure with reduced ejection fraction (HFrEF) mortality and readmissions. From a prospective multicenter registry that included 1831 patients hospitalized due to heart failure, 583 had a left ventricular ejection fraction of <40%. In total, 266 patients (45.6%) had coronary artery disease as main etiology and 137 (23.5%) had idiopathic dilated cardiomyopathy (DCM), and they are the focus of this study. Significant differences were found in Charlson index (CAD 4.4 +/- 2.8, idiopathic DCM 2.9 +/- 2.4, p < 0.001), and in the number of previous hospitalizations (1.1 +/- 1, 0.8 +/- 1.2, respectively, p = 0.015). One-year mortality was similar in the two groups: idiopathic DCM (hazard ratio [HR] = 1), CAD (HR 1.50; 95% CI 0.83-2.70, p = 0.182). Mortality/readmissions were also comparable: CAD (HR 0.96; 95% CI 0.64-1.41, p = 0.81). Patients with idiopathic DCM had a higher probability of receiving a heart transplant than those with CAD (HR 4.6; 95% CI 1.4-13.4, p = 0.012). The prognosis of HFrEF is similar in patients with CAD etiology and in those with idiopathic DCM. Patients with idiopathic DCM were more prone to receive heart transplant.

引用

页数：10

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