A Monte Carlo study on dose distribution of an orthovoltage radiation therapy system

被引：2

作者：

Iseri, Toshie ^{[1
]}

Tanabe, Yoshinori ^{[2
]}

Onizuka, Ryouta ^{[3
]}

Torigoe, Yuri ^{[1
]}

Horikirizono, Hiro ^{[1
]}

Itamoto, Kazuhito ^{[4
]}

Sunahara, Hiroshi ^{[5
]}

Itoh, Harumichi ^{[4
]}

Tani, Kenji ^{[5
]}

Nakaichi, Munekazu ^{[1
]}

机构：

[1] Yamaguchi Univ, Joint Fac Vet Med, Dept Vet Radiol, 1677-1 Yoshida, Yamaguchi, Yamaguchi, Japan

[2] Okayama Univ, Grad Sch Hlth Sci, Okayama, Japan

[3] Yamaguchi Univ, Dept Therapeut Radiol, Yamaguchi, Japan

[4] Yamaguchi Univ, Joint Fac Vet Med, Anim Med Ctr, Yamaguchi, Japan

[5] Yamaguchi Univ, Joint Fac Vet Med, Dept Vet Surg, Yamaguchi, Japan

来源：

PHYSICAL AND ENGINEERING SCIENCES IN MEDICINE | 2023年 / 46卷 / 02期

关键词：

Radiation treatment; Monte Carlo method; Radiotherapy dosage; Organs at risk; RADIOTHERAPY; KV;

D O I：

10.1007/s13246-023-01237-4

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

It is important to plan radiotherapy treatment and establish optimal dose distribution to reduce the chances of side effects and injury. Because there are no commercially available tools for calculating dose distribution in orthovoltage radiotherapy in companion animals, we developed an algorithm to accomplish this and verified its characteristics using tumor disease cases. First, we used the Monte Carlo method to develop an algorithm to calculate the dose distribution of orthovoltage radiotherapy (280 kVp; MBR-320, Hitachi Medical Corporation, Tokyo, Japan) using BEAMnrc at our clinic. Using development of Monte Carlo method, dose distribution for tumor and normal organs were evaluated in brain tumors, squamous cell carcinomas of the head, and feline nasal lymphomas. In all cases of brain tumors, the mean dose delivered to the GTV ranged from 36.2 to 76.1% of the prescribed dose due to the decrease through the skull. In the nasal lymphoma in cats, the eyes with covered a 2 mm-thick lead plate, the respective average dose to the eyes was 71.8% and 89.9% less than that to the uncovered eyes. The findings may be useful for informed decision making in orthovoltage radiotherapy with more effective and targeted irradiation and data collection allowing detailed informed consent.

引用

页码：623 / 632

页数：10

共 20 条

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