A Review of Applications of Solid-State Nuclear Magnetic Resonance (ssNMR) for the Analysis of Cyclodextrin-Including Systems

被引:19
作者
Mazurek, Anna Helena [1 ,2 ]
Szeleszczuk, Lukasz [1 ]
机构
[1] Med Univ Warsaw, Fac Pharm, Dept Organ & Phys Chem, Banacha 1 Str, PL-02093 Warsaw, Poland
[2] Med Univ Warsaw, Doctoral Sch, Zwirki & Wigury 81 Str, PL-02093 Warsaw, Poland
关键词
cyclodextrin; ssNMR; drug carrier; BETA-CYCLODEXTRIN; INCLUSION COMPLEXES; STRUCTURAL-CHARACTERIZATION; DYNAMIC PROPERTIES; FAST ADSORPTION; HYDROGEL FILMS; P-NITROPHENOL; NMR; POLYMER; CRYSTALLINE;
D O I
10.3390/ijms24043648
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cyclodextrins, cyclic oligosaccharides composed of five or more alpha-D-glucopyranoside units linked by alpha-1,4 glycosidic bonds, are widely used both in their native forms as well as the components of more sophisticated materials. Over the last 30 years, solid-state nuclear magnetic resonance (ssNMR) has been used to characterize cyclodextrins (CDs) and CD-including systems, such as host-guest complexes or even more sophisticated macromolecules. In this review, the examples of such studies have been gathered and discussed. Due to the variety of possible ssNMR experiments, the most common approaches have been presented to provide the overview of the strategies employed to characterize those useful materials.
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页数:21
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