New diagnostic criteria (2023) for slowly progressive type 1 diabetes (SPIDDM): Report from Committee on Type 1 Diabetes of the Japan Diabetes Society (English version)

被引：7

作者：

Shimada, Akira ^{[1
]}

Kawasaki, Eiji ^{[2
]}

Abiru, Norio ^{[3
]}

Awata, Takuya ^{[4
]}

Oikawa, Yoichi ^{[1
]}

Osawa, Haruhiko ^{[5
]}

Kajio, Hiroshi ^{[6
]}

Kozawa, Junji ^{[7
]}

Takahashi, Kazuma ^{[8
]}

Chujo, Daisuke ^{[9
]}

Noso, Shinsuke ^{[10
]}

Fukui, Tomoyasu ^{[11
]}

Miura, Junnosuke ^{[12
]}

Yasuda, Kazuki ^{[13
]}

Yasuda, Hisafumi ^{[14
]}

Imagawa, Akihisa ^{[15
]}

Ikegami, Hiroshi ^{[10
]}

机构：

[1] Saitama Med Univ, Sch Med, Dept Endocrinol & Diabet, Saitama, Japan

[2] Shin Koga Hosp, Diabet Ctr, Fukuoka, Japan

[3] Midori Clin, Nagasaki, Japan

[4] Natl Ctr Global Hlth & Med, Pancreat Islet Cell Transplantat Ctr, Tokyo, Japan

[5] Ehime Univ, Grad Sch Med, Dept Diabet & Mol Genet, Matsuyama, Ehime, Japan

[6] Natl Ctr Global Hlth & Med, Ctr Hosp, Dept Diabet Endocrinol & Metab, Tokyo, Japan

[7] Osaka Univ, Grad Sch Med, Dept Diabet Care Med, Osaka, Japan

[8] Iwate Prefectural Univ, Sch Nursing, Dept Basic Nursing Sci, Takizawa, Iwate, Japan

[9] Toyama Univ Hosp, Ctr Clin Res, Toyama, Japan

[10] Kindai Univ, Fac Med, Dept Endocrinol Metab & Diabet, Osaka, Japan

[11] Showa Univ, Sch Med, Dept Med, Div Diabet Metab & Endocrinol, Tokyo, Japan

[12] Tokyo Womens Med Univ, Sch Med, Dept Internal Med, Div Diabetol & Metab, Tokyo, Japan

[13] Kyorin Univ, Sch Med, Dept Diabet Endocrinol & Metab, Tokyo, Japan

[14] Kobe Univ, Dept Publ Hlth, Div Hlth Sci, Grad Sch Hlth Sci, Kobe, Hyogo, Japan

[15] Osaka Med & Pharmaceut Univ, Fac Med, Dept Internal Med 1, Osaka, Japan

来源：

JOURNAL OF DIABETES INVESTIGATION | 2024年

关键词：

GAD antibody; Latent autoimmune diabetes in adults; Slowly progressive type 1 diabetes; MELLITUS;

D O I：

10.1111/jdi.14121

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The diagnostic criteria for slowly progressive type 1 diabetes (slowly progressive insulin-dependent diabetes mellitus; SPIDDM) have been revised by the Committee on Type 1 Diabetes of the Japan Diabetes Society. All of the following three criteria must be met for 'a definitive diagnosis of SPIDDM': (1) presence of anti-islet autoantibodies at some point in time during the disease course; (2) absence of ketosis or ketoacidosis at the diagnosis of diabetes with no requirement for insulin treatment to correct hyperglycemia immediately after diagnosis in principle; and (3) gradual decrease of insulin secretion over time, with insulin treatment required at more than 3 months after diagnosis, and the presence of severe endogenous insulin deficiency (fasting serum C-peptide immunoreactivity <0.6 ng/mL) at the last observed point in time. When a patient fulfills only (1) and (2), but not (3), he/she is diagnosed with 'SPIDDM (probable)' because the diabetes is non-insulin-dependent type.

引用

页码：254 / 257

页数：4

共 13 条

[1] Possible Long-Term Efficacy of Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, for Slowly Progressive Type 1 Diabetes (SPIDDM) in the Stage of Non-Insulin-Dependency: An Open-Label Randomized Controlled Pilot Trial (SPAN-S)
Awata, Takuya
Shimada, Akira
Maruyama, Taro
Oikawa, Yoichi
Yasukawa, Nobuyuki
Kurihara, Susumu
Miyashita, Yumi
Hatano, Masako
Ikegami, Yuichi
Matsuda, Masafumi
Niwa, Masataka
Kazama, Youichiro
Tanaka, Shoichiro
Kobayashi, Tetsuro
[J]. DIABETES THERAPY, 2017, 8 (05) : 1123 - 1134
[2] Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel
Buzzetti, Raffaella
Tuomi, Tiinamaija
Mauricio, Didac
Pietropaolo, Massimo
Zhou, Zhiguang
Pozzilli, Paolo
Leslie, Richard David
[J]. DIABETES, 2020, 69 (10) : 2037 - 2047
[3] Diagnostic criteria for acute-onset type 1 diabetes mellitus (2012): Report of the Committee of Japan Diabetes Society on the Research of Fulminant and Acute-onset Type 1 Diabetes Mellitus
Kawasaki E.
Maruyama T.
Imagawa A.
Awata T.
Ikegami H.
Uchigata Y.
Osawa H.
Kawabata Y.
Kobayashi T.
Shimada A.
Shimizu I.
Takahashi K.
Nagata M.
Makino H.
Hanafusa T.
[J]. Diabetology International, 2013, 4 (4) : 221 - 225
[4] IMMUNOGENETIC AND CLINICAL CHARACTERIZATION OF SLOWLY PROGRESSIVE IDDM
KOBAYASHI, T
TAMEMOTO, K
NAKANISHI, K
KATO, N
OKUBO, M
KAJIO, H
SUGIMOTO, T
MURASE, T
KOSAKA, K
[J]. DIABETES CARE, 1993, 16 (05) : 780 - 788
[5] Insulin intervention in slowly progressive insulin-dependent (type 1) diabetes mellitus
Maruyama, Taro
Tanaka, Shoichiro
Shimada, Akira
Funae, Osamu
Kasuga, Akira
Kanatsuka, Azuma
Takei, Izumi
Yamada, Satoru
Harii, Norikazu
Shimura, Hiroki
Kobayashi, Tetsuro
[J]. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2008, 93 (06) : 2115 - 2121
[6] Slowly Progressive Type 1 Diabetes Mellitus: Current Knowledge And Future Perspectives
Nishimura, Akihiro
Matsumura, Kimio
Kikuno, Shota
Nagasawa, Kaoru
Okubo, Minoru
Mori, Yasumichi
Kobayashi, Tetsuro
[J]. DIABETES METABOLIC SYNDROME AND OBESITY-TARGETS AND THERAPY, 2019, 12 : 2461 - 2477
[7] Rajkumar V., 2022, StatPearls [Internet]. Treasure Island
[8] Heterogeneity and endotypes in type 1 diabetes mellitus
Redondo, Maria J.
Morgan, Noel G.
[J]. NATURE REVIEWS ENDOCRINOLOGY, 2023, 19 (09) : 542 - 554
[9] Shimada A., 2023, J Jpn Diabetes Soc, V66, P587
[10] Diagnostic criteria for slowly progressive insulin-dependent (type 1) diabetes mellitus (SPIDDM) (2012): report by the Committee on Slowly Progressive Insulin-Dependent (Type 1) Diabetes Mellitus of the Japan Diabetes Society
Tanaka S.
Ohmori M.
Awata T.
Shimada A.
Murao S.
Maruyama T.
Kamoi K.
Kawasaki E.
Nakanishi K.
Nagata M.
Fujii S.
Ikegami H.
Imagawa A.
Uchigata Y.
Okubo M.
Osawa H.
Kajio H.
Kawaguchi A.
Kawabata Y.
Satoh J.
Shimizu I.
Takahashi K.
Makino H.
Iwahashi H.
Miura J.
Yasuda K.
Hanafusa T.
Kobayashi T.
[J]. Diabetology International, 2015, 6 (1) : 1 - 7

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