Resorption Dynamics of Hydroxyapatite-, Wollastonite-, and Gelatin-Based Granules in Tris-Buffer

被引：0

作者：

Solonenko, A. P. ^{[1
]}

Shevchenko, A. E. ^{[1
]}

Polonyankin, D. A. ^{[2
]}

机构：

[1] Omsk State Med Univ, Omsk 644099, Russia

[2] Omsk State Tech Univ, Omsk 644050, Russia

来源：

INORGANIC MATERIALS | 2023年 / 59卷 / 03期

关键词：

biomaterials; dissolution; granulated materials; calcium phosphates; calcium silicates; COMPOSITE POWDERS; BIOACTIVITY;

D O I：

10.1134/S0020168523030147

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Results of an in vitro study demonstrate that, when brought in contact with tris-buffer, granules based on gelatin and synthetic ceramic powders containing varied percentages of Ca-10(PO4)(6)(OH)(2) and beta-CaSiO3 rapidly degrade and swell, increasing in size by up to a factor of 1.2. After that, they gradually degrade, releasing calcium ions and phosphate and silicate anions to the solution. The systems with materials containing 20 to 60 wt % calcium silicate have been found to differ little in the concentrations of these ions. The weight loss of the composites, due to dissolution of the mineral components and gelatin, has been shown to exceed that of the apatite and wollastonite granules.

引用

页码：329 / 336

页数：8