Mindfulness-based therapy improves brain functional network reconfiguration efficiency

被引:9
作者
Yue, Wan Lin [1 ,2 ,3 ]
Ng, Kwun Kei [1 ,2 ]
Koh, Amelia Jialing [1 ,2 ]
Perini, Francesca [1 ,2 ]
Doshi, Kinjal [4 ]
Zhou, Juan Helen [1 ,2 ,3 ,5 ]
Lim, Julian [1 ,2 ,6 ]
机构
[1] Natl Univ Singapore, Ctr Sleep & Cognit, Yong Loo Lin Sch Med, Singapore, Singapore
[2] Natl Univ Singapore, Ctr Translat Magnet Resonance Res, Yong Loo Lin Sch Med, Singapore, Singapore
[3] Natl Univ Singapore, NUS Grad Sch, Integrat Sci & Engn Programme, Singapore, Singapore
[4] Singapore Gen Hosp, Dept Psychol, Singapore, Singapore
[5] Natl Univ Singapore, Dept Elect & Comp Engn, Singapore, Singapore
[6] Natl Univ Singapore, Dept Psychol, Singapore, Singapore
基金
新加坡国家研究基金会;
关键词
DEFAULT-MODE NETWORK; INSOMNIA SEVERITY INDEX; WORKING-MEMORY CAPACITY; SLEEP QUALITY; OLDER-ADULTS; CARDIOVASCULAR-DISEASE; FOCUSED ATTENTION; STRESS REDUCTION; MEDITATION; CONNECTIVITY;
D O I
10.1038/s41398-023-02642-9
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Mindfulness-based interventions are showing increasing promise as a treatment for psychological disorders, with improvements in cognition and emotion regulation after intervention. Understanding the changes in functional brain activity and neural plasticity that underlie these benefits from mindfulness interventions is thus of interest in current neuroimaging research. Previous studies have found functional brain changes during resting and task states to be associated with mindfulness both cross-sectionally and longitudinally, particularly in the executive control, default mode and salience networks. However, limited research has combined information from rest and task to study mindfulness-related functional changes in the brain, particularly in the context of intervention studies with active controls. Recent work has found that the reconfiguration efficiency of brain activity patterns between rest and task states is behaviorally relevant in healthy young adults. Thus, we applied this measure to investigate how mindfulness intervention changed functional reconfiguration between rest and a breath-counting task in elderly participants with self-reported sleep difficulties. Improving on previous longitudinal designs, we compared the intervention effects of a mindfulness-based therapy to an active control (sleep hygiene) intervention. We found that mindfulness intervention improved self-reported mindfulness measures and brain functional reconfiguration efficiency in the executive control, default mode and salience networks, though the brain and behavioral changes were not associated with each other. Our findings suggest that neuroplasticity may be induced through regular mindfulness practice, thus bringing the intrinsic functional configuration in participants' brains closer to a state required for mindful awareness.
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页数:10
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共 132 条
  • [1] Cognitive-Affective Neural Plasticity following Active-Controlled Mindfulness Intervention
    Allen, Micah
    Dietz, Martin
    Blair, Karina S.
    van Beek, Martijn
    Rees, Geraint
    Vestergaard-Poulsen, Peter
    Lutz, Antoine
    Roepstorff, Andreas
    [J]. JOURNAL OF NEUROSCIENCE, 2012, 32 (44) : 15601 - 15610
  • [2] Mechanisms of mindfulness: Emotion regulation following a focused breathing induction
    Arch, Joanna J.
    Craske, Michelle G.
    [J]. BEHAVIOUR RESEARCH AND THERAPY, 2006, 44 (12) : 1849 - 1858
  • [3] Using self-report assessment methods to explore facets of mindfulness
    Baer, RA
    Smith, GT
    Hopkins, J
    Krietemeyer, J
    Toney, L
    [J]. ASSESSMENT, 2006, 13 (01) : 27 - 45
  • [4] Mindfulness-based cognitive therapy as a treatment for chronic depression: A preliminary study
    Barnhofer, Thorsten
    Crane, Catherine
    Hargus, Emily
    Amarasinghe, Myanthi
    Winder, Rosie
    Williams, J. Mark G.
    [J]. BEHAVIOUR RESEARCH AND THERAPY, 2009, 47 (05) : 366 - 373
  • [5] Validation of the Insomnia Severity Index as an outcome measure for insomnia research
    Bastien, Celyne H.
    Vallieres, Annie
    Morin, Charles M.
    [J]. SLEEP MEDICINE, 2001, 2 (04) : 297 - 307
  • [6] Mindfulness training preserves sustained attention and resting state anticorrelation between default-mode network and dorsolateral prefrontal cortex: A randomized controlled trial
    Bauer, Clemens C. C.
    Rozenkrantz, Liron
    Caballero, Camila
    Nieto-Castanon, Alfonso
    Scherer, Ethan
    West, Martin R.
    Mrazek, Michael
    Phillips, Dawa T.
    Gabrieli, John D. E.
    Whitfield-Gabrieli, Susan
    [J]. HUMAN BRAIN MAPPING, 2020, 41 (18) : 5356 - 5369
  • [7] Depression and sleep quality in older adults: a meta-analysis
    Becker, Nathalia B.
    Jesus, Saul N.
    Joao, Karine A. D. R.
    Viseu, Joao N.
    Martins, Rute I. S.
    [J]. PSYCHOLOGY HEALTH & MEDICINE, 2017, 22 (08) : 889 - 895
  • [8] The Assessment of Mindfulness with Self-Report Measures: Existing Scales and Open Issues
    Bergomi, Claudia
    Tschacher, Wolfgang
    Kupper, Zeno
    [J]. MINDFULNESS, 2013, 4 (03) : 191 - 202
  • [9] Alterations in task-induced activity and resting-state fluctuations in visual and DMN areas revealed in long-term meditators
    Berkovich-Ohana, Aviva
    Harel, Michal
    Hahamy, Avital
    Arieli, Amos
    Malach, Rafael
    [J]. NEUROIMAGE, 2016, 135 : 125 - 134
  • [10] Mindfulness Meditation and Improvement in Sleep Quality and Daytime Impairment Among Older Adults With Sleep Disturbances A Randomized Clinical Trial
    Black, David S.
    O'Reilly, Gillian A.
    Olmstead, Richard
    Breen, Elizabeth C.
    Irwin, Michael R.
    [J]. JAMA INTERNAL MEDICINE, 2015, 175 (04) : 494 - 501