MSA-VT Score for Assessment of Long-Term Prognosis after Electrical Storm Ablation

被引:2
作者
Vatasescu, Radu [1 ,2 ]
Cojocaru, Cosmin [1 ,2 ]
Gondos, Viviana [3 ]
Iorgulescu, Corneliu [2 ]
Bogdan, Stefan [1 ,4 ]
Onciul, Sebastian [1 ,2 ]
Berruezo, Antonio [5 ]
机构
[1] Carol Davila Univ Med & Pharm, Fac Med, Dept Cardiothorac Pathol, Bucharest 050474, Romania
[2] Clin Emergency Hosp Bucharest, Cardiol Dept, Bucharest 014461, Romania
[3] Polytech Univ, Dept Med Elect & Informat, Bucharest 060042, Romania
[4] Elias Univ, Emergency Hosp, Cardiol Dept, Bucharest 011461, Romania
[5] Teknon Med Ctr, Heart Inst, C Vilana,12, Barcelona 08022, Spain
关键词
electrical storm; catheter ablation; risk assessment; mortality; recurrence; VENTRICULAR-TACHYCARDIA; CATHETER ABLATION; AMERICAN SOCIETY; SUBSTRATE; OUTCOMES; ECHOCARDIOGRAPHY; RECOMMENDATIONS; DEFIBRILLATOR; PREDICTORS; MORTALITY;
D O I
10.3390/biomedicines12030493
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Introduction: Prognosis after electrical storm (ES) ablation remains severe, especially in patients with recurrent sustained monomorphic ventricular tachycardia (SMVT) or progressive heart failure (HF). However, single-factor-based prediction is suboptimal and may be refined by more complex algorithms. We sought to evaluate if a novel score MSA-VT (M = moderate/severe mitral regurgitation, S = severe HF at admission, A = atrial fibrillation at admission, VT = inducible SMVT after ablation) may improve prediction of death and recurrences compared to single factors and previous scores (PAINESD, RIVA and I-VT). Methods: A total of 101 consecutive ES ablation patients were retrospectively analyzed over a 32.8-month (IQR 10-68) interval. The MSA-VT score was calculated as the sum of the previously mentioned factors' coefficients based on hazard ratio values in Cox regression analysis. The AUC for death prediction by MSA-VT was 0.84 (p < 0.001), superior to PAINESD (AUC 0.63, p = 0.03), RIVA (AUC 0.69, p = 0.02) and I-VT (0.56, p = 0.3). MSA-VT >= 3 was associated with significantly higher mortality during follow-up (52.7%, p < 0.001). Conclusions: Prediction by single factors and previously published scores after ES ablation may be improved by the novel MSA-VT score; however, this requires further external validation in larger samples.
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页数:12
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