A case of radiotherapy-induced bullous pemphigoid with unusually delayed onset: A case report

被引:0
作者
El Barch, Maha [1 ,3 ]
Davar, Sandra [1 ]
Belisle, Annie [2 ]
机构
[1] Ctr Hosp Univ Montreal CHUM, Dept Med, Div Dermatol, Montreal, PQ, Canada
[2] Ctr Hosp Univ Montreal CHUM, Dept Pathol, Montreal, PQ, Canada
[3] Ctr Hosp Univ Montreal CHUM, Dept Med, Div Dermatol, 1051 Rue Sanguinet, Montreal, PQ H2X 0C1, Canada
来源
SAGE OPEN MEDICAL CASE REPORTS | 2023年 / 11卷
关键词
Bullous pemphigoid; radiotherapy; auto-immune bullous disease; RADIATION-THERAPY;
D O I
10.1177/2050313X231212991
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Bullous pemphigoid is an auto-immune blistering disease that generally affects older patients. Radiotherapy is one of the many triggering factors that have been described. Time to disease onset is variable; cases have been described during the course of radiotherapy while others have occurred up to 9 years later. We report a case of localized bullous pemphigoid on an irradiated site with unusual late presentation, 25 years after radiotherapy for left breast cancer. The pathophysiology of radiation-induced bullous pemphigoid is not clear, but the concept of an immunocompromised district seems to be a plausible explanation for the delayed onset of the disease.
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页数:3
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共 9 条
  • [1] Localized bullous pemphigoid occurring on surgical scars: An instance of immunocompromised district
    Baroni, Adone
    Piccolo, Vincenzo
    Russo, Teresa
    Chessa, Marco Adriano
    [J]. INDIAN JOURNAL OF DERMATOLOGY VENEREOLOGY & LEPROLOGY, 2014, 80 (03) : 255 - 255
  • [2] BULLOUS PEMPHIGOID AFTER RADIATION-THERAPY
    DUSCHET, P
    SCHWARZ, T
    GSCHNAIT, F
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 1988, 18 (02) : 441 - 444
  • [3] Miyamoto D, 2019, AN BRAS DERMATOL, V94, P133
  • [4] Bullous Pemphigoid: Trigger and Predisposing Factors
    Moro, Francesco
    Fania, Luca
    Sinagra, Jo Linda Maria
    Salemme, Adele
    Di Zenzo, Giovanni
    [J]. BIOMOLECULES, 2020, 10 (10) : 1 - 29
  • [5] Radiation-induced bullous pemphigoid: A systematic review of an unusual radiation side effect
    Mul, Veronique E. M.
    van Geest, Adrienne J.
    Pijls-Johannesma, Madelon C. G.
    Theys, Jan
    Verschueren, Tom A. M.
    Jager, Jos J.
    Lambin, Philippe
    Baumert, Brigitta G.
    [J]. RADIOTHERAPY AND ONCOLOGY, 2007, 82 (01) : 5 - 9
  • [6] Bullous pemphigoid and radiotherapy: case report and literature review update
    Piras, Antonio
    Fionda, Bruno
    Sanfratello, Antonella
    D'Aviero, Andrea
    Sortino, Giovanni
    Pernice, Gianfranco
    Boldrini, Luca
    Angileri, Tommaso
    Daidone, Antonino
    [J]. DERMATOLOGY REPORTS, 2022, 14 (02)
  • [7] LONG-TERM EFFECTS ON THE IMMUNE SYSTEM FOLLOWING LOCAL RADIATION-THERAPY FOR BREAST-CANCER .1. CELLULAR COMPOSITION OF THE PERIPHERAL-BLOOD LYMPHOCYTE POPULATION
    ROTSTEIN, S
    BLOMGREN, H
    PETRINI, B
    WASSERMAN, J
    BARAL, E
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1985, 11 (05): : 921 - 925
  • [8] The immunocompromised district: a unifying concept for lymphoedematous, herpes-infected and otherwise damaged sites
    Ruocco, V.
    Brunetti, G.
    Puca, R. V.
    Ruocco, E.
    [J]. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY, 2009, 23 (12) : 1364 - 1373
  • [9] Relationship between Radiation Therapy and Bullous Pemphigoid
    Tegan Nguyen
    Kwan, Julia M.
    Ahmed, A. Razzaque
    [J]. DERMATOLOGY, 2014, 229 (02) : 88 - 96