Emergence of melioidosis in Brazil: a case series

被引:0
作者
Veloso, Dilbert Silva [1 ,3 ]
da Silva, Samuel Pinheiro [1 ]
de Coelho, Conceicao Maria Sousa [1 ]
Parente, Jose Miguel Luz [1 ]
Veloso, Thaline Alves Elias [1 ]
Lima, Murilo Moura [1 ]
Sampaio, Caroline Torres [1 ]
de Freitas, Maria Fatima Alencar Bezerra [1 ]
Rolim, Dionne Bezerra [2 ]
de Lemos, Elba Regina Sampaio [3 ]
Horta, Marco Aurelio Pereira [3 ]
机构
[1] Univ Fed Piaui, Univ Hosp, Teresina, Brazil
[2] Univ Fed Ceara, Fortaleza, Brazil
[3] Fundacao Oswaldo Cruz, Lab Hantaviroses & Rickettsioses, Inst Oswaldo Cruz, Rio De Janeiro, Brazil
关键词
Burkholderia pseudomallei; Melioidosis; Brazil;
D O I
10.1186/s13256-023-04093-8
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BackgroundMelioidosis is a serious disease caused by the bacterium Burkholderia pseudomallei which affects humans and animals. It results in a wide spectrum of clinical manifestations, mainly in the respiratory tract, progressing to septic shock and death.Case presentationHerein, we present a series of seven patients (median age: 41 years) with confirmed melioidosis, treated at a public hospital in Piaui State, Brazil between 2019 and 2021. The most common clinical presentations were fever, cough, pneumonia, and abdominal pain. The mean duration of antibacterial therapy with 1 g of meropenem was 28.6 & PLUSMN; 1.1 days. Six patients recovered and one died. The mean hospitalization time was 51.0 & PLUSMN; 39.2 days.ConclusionsMelioidosis is an emerging infectious disease in Brazil. Health professionals in endemic areas need to be aware of the clinical presentation and appropriate clinical management of the disease because early diagnosis and early initiation of antibiotic therapy can be life-saving.
引用
收藏
页数:5
相关论文
共 11 条
[1]   The Epidemiology and Clinical Spectrum of Melioidosis: 540 Cases from the 20 Year Darwin Prospective Study [J].
Currie, Bart J. ;
Ward, Linda ;
Cheng, Allen C. .
PLOS NEGLECTED TROPICAL DISEASES, 2010, 4 (11)
[2]   Ecology of Burkholderia pseudomallei and the interactions between environmental Burkholderia spp. and human-animal hosts [J].
Dance, DAB .
ACTA TROPICA, 2000, 74 (2-3) :159-168
[3]   Melioidosis: clinical aspects [J].
Karunanayake, Panduka .
CLINICAL MEDICINE, 2022, 22 (01) :6-8
[4]   Pitfalls and optimal approaches to diagnose melioidosis [J].
Kingsley, Paul Vijay ;
Arunkumar, Govindakarnavar ;
Tipre, Meghan ;
Leader, Mark ;
Sathiakumar, Nalini .
ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2016, 9 (06) :515-524
[5]   Genitourinary melioidosis: a descriptive study [J].
Koshy, Maria ;
Sadanshiv, Prashansa ;
Sathyendra, Sowmya .
TROPICAL DOCTOR, 2019, 49 (02) :104-107
[6]  
Limmathurotsakul D, 2016, NAT MICROBIOL, V1, DOI [10.1038/nmicrobiol.2015.8, 10.1038/NMICROBIOL.2015.8]
[7]   Increasing Incidence of Human Melioidosis in Northeast Thailand [J].
Limmathurotsakul, Direk ;
Wongratanacheewin, Surasakdi ;
Teerawattanasook, Nittaya ;
Wongsuvan, Gumphol ;
Chaisuksant, Seksan ;
Chetchotisakd, Ploenchan ;
Chaowagul, Wipada ;
Day, Nicholas P. J. ;
Peacock, Sharon J. .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2010, 82 (06) :1113-1117
[8]  
Menon Raviraj, 2021, ScientificWorldJournal, V2021, P8154810, DOI 10.1155/2021/8154810
[9]   Acute kidney injury and its outcomes in melioidosis [J].
Prabhu, Ravindra Attur ;
Shaw, Tushar ;
Rao, Indu Ramachandra ;
Eshwara, Vandana Kalwaje ;
Nagaraju, Shankar Prasad ;
Shenoy, Srinivas Vinayak ;
Mukhopadhyay, Chiranjay .
JOURNAL OF NEPHROLOGY, 2021, 34 (06) :1941-1948
[10]   Melioidosis, northeastern Brazil [J].
Rolim, DB ;
Vilar, DCFL ;
Sousa, AQ ;
Miralles, IS ;
de Oliveira, DCA ;
Harnett, G ;
O'Reilly, L ;
Howard, K ;
Sampson, I ;
Inglis, TJJ .
EMERGING INFECTIOUS DISEASES, 2005, 11 (09) :1458-1460