Three-component reaction for the synthesis of imides enabled by electrochemical C(sp3)-H functionalization

被引：10

作者：

Chu, Qiao ^{[1
]}

Feng, Zhaoyue ^{[1
]}

Zhang, Sumin ^{[1
]}

Liu, Ping ^{[1
]}

Sun, Peipei ^{[1
]}

机构：

[1] Nanjing Normal Univ, Jiangsu Collaborat Innovat Ctr Biomed Funct Mat, Sch Chem & Mat Sci, Jiangsu Prov Key Lab Mat Cycle Proc & Pollut Contr, Nanjing 210023, Peoples R China

来源：

GREEN CHEMISTRY | 2023年 / 25卷 / 17期

基金：

中国国家自然科学基金;

关键词：

CONJUGATE ADDITION; CYCLIC IMIDES; NITRILES; AMIDES;

D O I：

10.1039/d3gc02174b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An electrochemical three-component reaction cascade Mumm rearrangement was developed for the synthesis of imides. Commercially available aryl acids, nitriles, and alkylbenzenes were used as substrates without pre-functionalization, and the reactions were conducted under transition metal- and chemical oxidant-free conditions. Subsequent hydrolysis or reduction of the imide products could be easily achieved to synthesize amides, as well as primary or tertiary amines.

引用

页码：6728 / 6732

页数：5

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