Exploring the potential function of trace elements in human health: a therapeutic perspective

被引:86
作者
Islam, Md. Rezaul [1 ]
Akash, Shopnil [1 ]
Jony, Maruf Hossain [1 ]
Alam, Md. Noor [1 ]
Nowrin, Feana Tasmim [1 ]
Rahman, Md. Mominur [1 ]
Rauf, Abdur [2 ]
Thiruvengadam, Muthu [3 ,4 ]
机构
[1] Daffodil Int Univ, Fac Allied Hlth Sci, Dept Pharm, Dhaka 1207, Bangladesh
[2] Univ Swabi, Dept Chem, Anbar, Khyber Pakhtunk, Pakistan
[3] Konkuk Univ, Coll Life & Environm Sci, Dept Appl Biosci, Seoul 05029, South Korea
[4] Saveetha Inst Med & Tech Sci, Saveetha Dent Coll & Hosp, Dept Microbiol, Chennai 600077, Tamil Nadu, India
关键词
Health; Micro-nutrients; Body function; Trace elements; Diseases; Enzymes; INFLAMMATORY-BOWEL-DISEASE; IMMUNODEFICIENCY-VIRUS TYPE-1; SUPEROXIDE-DISMUTASE ACTIVITY; INDUCED COPPER DEFICIENCY; ZINC-DEFICIENCY; OXIDATIVE STRESS; LIPID-PEROXIDATION; GENE-EXPRESSION; HEMODIALYSIS-PATIENTS; EXPERIMENTAL COLITIS;
D O I
10.1007/s11010-022-04638-3
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
A trace element, known as a minor element, is a chemical element whose concentration is very low. They are divided into essential and non-essential classes. Numerous physiological and metabolic processes in both plants and animals require essential trace elements. These essential trace elements are so directly related to the metabolic and physiologic processes of the organism that either their excess or deficiency can result in severe bodily malfunction or, in the worst situations, death. Elements can be found in nature in various forms and are essential for the body to carry out its varied functions. Trace elements are crucial for biological, chemical, and molecular cell activity. Nutritional deficits can lead to weakened immunity, increased susceptibility to oral and systemic infections, delayed physical and mental development, and lower productivity. Trace element enzymes are involved in many biological and chemical processes. These compounds act as co-factors for a number of enzymes and serve as centers for stabilizing the structures of proteins and enzymes, allowing them to mediate crucial biological processes. Some trace elements control vital biological processes by attaching to molecules on the cell membrane's receptor site or altering the structure of the membrane to prevent specific molecules from entering the cell. Some trace elements are engaged in redox reactions. Trace elements have two purposes. They are required for the regular stability of cellular structures, but when lacking, they might activate alternate routes and induce disorders. Therefore, thoroughly understanding these trace elements is essential for maintaining optimal health and preventing disease.
引用
收藏
页码:2141 / 2171
页数:31
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