Essential oil composition and biological activities of Aleppo pine (Pinus halepensis Miller) needles collected from different Tunisian regions

被引：8
作者：
Dakhlaoui, Sarra [1 ,2 ]
Bourgou, Soumaya [2 ]
Bachkouel, Sarra [3 ]
Ben Mansour, Rim [2 ]
Ben Jemaa, Mariem [2 ]
Jallouli, Slim [4 ]
Megdiche-Ksouri, Wided [2 ]
Hessini, Kamel [5 ]
Msaada, Kamel [2 ]
机构：
[1] Tunis El Manar Univ, Coll Sci Tunis, Tunis, Tunisia
[2] Biotechnol Ctr Borj Cedria Technopole, Lab Aromat & Med Plants LPAM, Hammam Lif 2050, Tunisia
[3] Ctr Biotechnol Borj Cedria, Espace Appui Rech & Transfert Technol ARTT, Hammam Lif, Tunisia
[4] Biotechnol Ctr Borj Cedria, Lab Bioact Subst LSBA, Hammam Lif, Tunisia
[5] Taif Univ, Coll Sci, Dept Biol, At Taif, Saudi Arabia
来源：
INTERNATIONAL JOURNAL OF ENVIRONMENTAL HEALTH RESEARCH | 2023年 / 33卷 / 01期
关键词：
Pinus halepensis; essential oil composition; antioxidant activities; anti-inflammatory activity; anti-diabetic activity; CHEMICAL-COMPOSITION; ANTIOXIDANT ACTIVITIES; BETA-CARYOPHYLLENE; ANTICHOLINESTERASE; ANTIBACTERIAL; SESQUITERPENE; VARIABILITY; ANTIFUNGAL; L;
D O I：
10.1080/09603123.2021.2005001
中图分类号：
X [环境科学、安全科学];
学科分类号：
08 ; 0830 ;
摘要：
The aim of this research was to investigate the variation regarding the chemical composition and biological activities of needles essential oils (EOs) of P. halepensis. Chemical profiles demonstrated a significant (P < 0.05) variability among the different EOs. The main identified compounds were caryophyllene (48.77 +/- 2.26), phenyl isovalerate (22.22 +/- 2.26), beta-myrcene (15.55 +/- 5.65) and alpha-pinene (14.52 +/- 2.26). Further, it was shown that EO from Tabouba (Tab) displayed the highest DPPH scavenging (IC50 = 73.03 mg/mL), anti-inflammatory (IC50 = 23.29 mu g/mL) and alpha-glucosidase inhibition activities (IC50 = 254.45 mu g/mL). While Elmahres (Elm) exhibited the most potent ABTS radical's inhibition (IC50 = 197.87 mg/mL). For the cytotoxic capacities, Kettana (Ket) was the most efficient against breast cancer MCF-7 cell line with IC50 value better than doxorubicin used as positive control. Obtained results suggest that EO of P. halepensis could be used as a source of bioactive compounds.
引用
收藏
页码：83 / 97
页数：15
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