Development of ligand-free Pd@TiO2 catalyst for efficient perfluoroalkylative carbonylation of terminal alkenes

The development of heterogeneous catalysts for the difunctionalization of olefins is of great scientific significance because of their sustainability in the manufacturing industry. Herein, we report a ligand free Pd@TiO2 catalyst that realized the perfluoroalkyl carbonylation of terminal olefins using carbon monoxide as the C1 source, providing sustainable access to beta-perfluoroalkyl esters. This catalyst shows high activity, good recyclability, and broad functional group tolerance. The catalytic system developed here can reduce noble metal use and avoid using precious homogeneous phosphorus ligands, which are also toxic to the environment.