Getting to know ovarian cancer: Focusing on the effect of LncRNAs in this cancer and the effective signaling pathways

被引：1

作者：

Alzahrani, Abdullah Ali ^{[1
]}

Almajidi, Yasir Qasim ^{[2
]}

Jasim, Saade Abdalkareem ^{[3
,14
]}

Hjazi, Ahmed ^{[4
]}

Olegovich, Bokov Dmitry ^{[5
,6
]}

Alkhafaji, Adnan Taan ^{[7
]}

Abdulridui, Hussam Abdali ^{[8
]}

Ahmed, Batool Ali ^{[9
]}

Alawadi, Ahmed ^{[10
,11
,12
]}

Alsalamy, Ali ^{[13
]}

机构：

[1] Taif Univets, Dept Surg, Taif, Saudi Arabia

[2] Baghdad Coll Med Sci, Dept Pharm, Baghdad, Iraq

[3] Al Maarif Univ Coll, Med Lab Tech Dept, Anbar, Iraq

[4] Prince Sattam Bin Abdulaziz Univ, Coll Appl Med Sci, Dept Med Lab Sci, Alkharj, Saudi Arabia

[5] Moscow Med Univ, Inst Pharm, Moscow, Russia

[6] Fed Res Ctr Nutr Biotechnol & Food Safety, Lab Food Chem, Moscow, Russia

[7] Al Ayen Univ, Coll Med, Cardiol Dept, Thi Qar, Iraq

[8] Al Hadi Univ Coll, Dept Med Engn, Baghdad, Iraq

[9] AL Nisour Univ Coll, Dept Med Engn, Baghdad, Iraq

[10] Islamic Univ, Coll Tech Engn, Najaf, Iraq

[11] Islamic Univ Al Diwaniyah, Coll Tech Engn, Al Diwaniyah, Iraq

[12] Islamic Univ Babylon, Coll Tech Engn, Babylon, Iraq

[13] Imam Jaafar Al Sadiq Univ, Coll Tech Engn, Al Muthanna, Iraq

[14] Baghdad Coll Med Sci, Dept Pharm, Baghdad, Iraq

来源：

PATHOLOGY RESEARCH AND PRACTICE | 2024年 / 254卷

关键词：

Ovarian cancers; LncRNAs; Signaling pathways; LncRNA; HOTAIR; POOLED ANALYSIS; POOR-PROGNOSIS; HOTAIR; RNA; EXPRESSION; CHEMORESISTANCE; ASSOCIATION; CONTRIBUTES; BIOMARKER; PROFILES;

D O I：

10.1016/j.prp.2023.155084

中图分类号：

R36 [病理学];

学科分类号：

100104 ;

摘要：

This article undertakes a comprehensive investigation of ovarian cancer, examining the complex nature of this challenging disease. The main focus is on understanding the role of long non-coding RNAs (lncRNAs) in the context of ovarian cancer (OC), and their regulatory functions in disease progression. Through extensive research, the article identifies specific lncRNAs that play significant roles in the intricate molecular processes of OC. Furthermore, the study examines the signaling pathways involved in the development of OC, providing a detailed comprehension of the underlying molecular mechanisms. By connecting lncRNA dynamics with signaling pathways, this exploration not only advances our understanding of ovarian cancer but also reveals potential targets for therapeutic interventions. The findings open up opportunities for targeted treatments, highlighting the importance of personalized approaches in addressing this complex disease and driving progress in ovarian cancer research and treatment strategies.

引用

页数：5

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