Natural Bioactive Compounds against Oxidative Stress: Dietary Polyphenols Strike Back

被引：6

作者：

Arrigoni, Roberto ^{[1
]}

Cammarota, Francesco ^{[2
]}

Porro, Rosa ^{[3
]}

Cantore, Stefania ^{[4
,11
]}

Dioguardi, Mario ^{[5
]}

Cazzolla, Angela Pia ^{[5
]}

De Leonardis, Francesco ^{[2
]}

Polimeno, Lorenzo ^{[6
]}

Zerman, Nicoletta ^{[7
]}

Di Cosola, Michele ^{[5
]}

Mastrangelo, Filiberto ^{[5
]}

Santacroce, Luigi ^{[8
]}

Ballini, Andrea ^{[9
,10
]}

机构：

[1] CNR, Inst Biomembranes Bioenerget & Mol Biotechnol IBIO, Bari, Italy

[2] Univ Bari, Dept Biosci Biotechnol & Biopharmaceut, Bari, Italy

[3] Univ Bari Aldo Moro, Dept Informat, Bari, Italy

[4] Sorriso & Benessere Ric & Clin, Bari, Italy

[5] Univ Foggia, Dept Clin & Expt Med, Foggia, Italy

[6] Univ Bari Aldo Moro, Sch Med, Polypheno Acad Spin Off, Bari, Italy

[7] Univ Verona, Dept Surg Dent Maternal & Child Sci, Verona, Italy

[8] Univ Bari Aldo Moro, Dept Interdisciplinary Med, Microbiol & Virol Unit, Bari, Italy

[9] Univ Aldo Moro, Bari, Italy

[10] Univ Campania Luigi Vanvitelli, Dept Precis Med, Naples, Italy

[11] Sorriso & Benessere Ric & Clin, I-70129 Bari, Italy

来源：

ENDOCRINE METABOLIC & IMMUNE DISORDERS-DRUG TARGETS | 2023年 / 23卷 / 06期

关键词：

Polyphenols; oxidative stress; natural compounds; anti-inflammatory activity; reactive oxygen species (ROS); polyphenol therapeutic potential; clinical studies; CATECHIN CONTENTS; DOWN-REGULATION; CANCER; ANTIOXIDANT; METABOLISM; CURCUMIN; ACTIVATION; EXPRESSION; MICRORNAS; APOPTOSIS;

D O I：

10.2174/1871530323666221107092553

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Oxidative stress is a major cellular and metabolic burden that can really alter cell life and become the base for disease onset and development. Many widespread pathologies can develop from an unresolved oxidative stress situation; thus, addressing this state is paramount for human health. Our antioxidant enzymes sometimes are not just enough. Fortifying our defense and the antioxidant and anti-inflammatory system can make a difference in our health: if this is attainable with our dietary habits, it could be a dream come true. Polyphenols are a fantastic tool indeed in the fight against oxidative stress: they are easy to obtain, with little cost, no side effects, and have a multitude of metabolic actions. This perspective review would shed light on polyphenol's metabolic and molecular action regarding oxidative stress to help preserve our health.

引用

页码：764 / 776

页数：13

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