Apoptotic, cytotoxic, antioxidant, and antibacterial activities of biosynthesized silver nanoparticles from nettle leaf

被引:9
作者
Daglioglu, Yesim [1 ]
Oztuerk, Betul Yilmaz [2 ]
Khatami, Mehrdad [3 ]
机构
[1] Ordu Univ, Mol Biol & Genet Dept, Ordu, Turkiye
[2] Eskisehir Osmangazi Univ, Cent Res Lab, Applicat & Res Ctr, Eskisehir, Turkiye
[3] Environm Res Ctr, Dept Environm Kerman, Kerman, Iran
关键词
antibacterial activity; anticancer activity; antioxidant activity; silver nanoparticles; Urtica dioica; MINIMUM QUANTITY LUBRICATION; ZINC-OXIDE NANOPARTICLES; ANTIFUNGAL ACTIVITY; GOLD NANOPARTICLES; GREEN SYNTHESIS; VEGETABLE-OIL; NANOFLUID; EXTRACT; CU; EFFICIENT;
D O I
10.1002/jemt.24306
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
Here, we reported the biosynthesis of silver nanoparticles (AgNPs) using Urtica dioica (nettle) leaf extract as green reducing and capping agents and investigate their anticancer and antibacterial, activity. The Nettle-mediated biosynthesized AgNPs was characterized by UV-Vis a spectrophotometer. Their size, shape and elemental analysis were determined with the using of SEM and TEM. The crystal structure was determined by XRD and the biomolecules responsible for the reduction of Ag+ were determined using FTIR analysis. Nettle-mediated biosynthesis AgNPs indicated strong antibacterial activity against pathogenic microorganisms. Again, the antioxidant activity of AgNPs is quite high when compared to ascorbic acid. Anticancer effect of AgNPs, IC50 dose was determined by XTT analysis using MCF-7 cell line and the IC50 value was found to be 0.243 +/- 0.014 mu g/mL (% w/v).
引用
收藏
页码:669 / 685
页数:17
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