Relationship between bronchial asthma and COVID-19 infection in adults: clinical and laboratory assessment

BackgroundAsthma is still considered a major chronic respiratory disease that affects a large number in the world. The association between COVID-19 infection and asthma was studied in different ways focusing on hospital-admitted patients. This study aimed to assess the outcome of patients with asthma and/or COVID infection in adults attending outpatient pulmonary clinic over three successive months from clinical and laboratory point of view.Patients and methodsThe current study was a retrospective observational study involving 898 patients attending the outpatient pulmonary clinic of a Saudi Arabian private hospital over three successive months from the 1st of December 2020 to the end of February 2021. Patients were divided into three groups: group 1-COVID-19 infected with asthma (312); group 2-COVID-19 infected with no asthma (286); and group 3-COVID-19 non-infected with asthma (300).Results and conclusionsResults showed the best patient's outcome was seen in asthmatic patients without COVID-19 infection followed by asthmatic patient with COVID-19 infection. There was a significant statistical difference in eosinophil count between COVID-19-infected patients with asthma and COVID-19 infected without asthma. Also, it was shown that the most common cause of hospitalization in asthmatic patients with COVID-19 infection was pneumonia followed by gastroenteritis and not an asthma exacerbation.